{"id":3941,"date":"2021-05-11T03:57:25","date_gmt":"2021-05-10T19:57:25","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3941"},"modified":"2021-05-11T03:57:25","modified_gmt":"2021-05-10T19:57:25","slug":"share-a-compound-73387-52-7","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3941","title":{"rendered":"Share a compound : 73387-52-7"},"content":{"rendered":"

Reference of 73387-52-7<\/a>, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 73387-52-7, name is 5-(4-Bromophenyl)-1-methyl-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows.<\/p>\n

In a 40 ml vial, bromo derivative (236 mg, 1.06 mmol, 1.0 eq.), bispinacolotodiboron (253.6 mg, 1.06 mmol, 1.0 eq.), Pd(dppf)CI2 (86.4 mg, 0.106 mmol, 0.1 eq.) and potassium acetate (321.8 mg, 3.17mmol, 3.0 eq.) were mixed in dioxane (10 ml) and heated to 80 C for 48 hours. LCMS indicated that the product was formed in major amount. . The crude reaction was purified in the presence of silica (10-15 gm) and purified using hexanes: ethyl acetate (0-100%) to yield desired boron ester. Theproduct was characterized by reverse phase HPLC using method 4. (ES, m\/z) [M +H+] 284.9. Retention time = 1.42 mins<\/p>\n

The chemical industry reduces the impact on the environment during synthesis 5-(4-Bromophenyl)-1-methyl-1H-pyrazole. I believe this compound will play a more active role in future production and life.<\/p>\n","protected":false},"excerpt":{"rendered":"

The chemical industry reduces the impact on the environment during synthesis 5-(4-Bromophenyl)-1-methyl-1H-pyrazole. I believe this compound will play a more active role in future production and life.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[611,131],"tags":[127],"class_list":["post-3941","post","type-post","status-publish","format-standard","hentry","category-73387-52-7","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nShare a compound : 73387-52-7<\/title>\n<meta name=\"description\" content=\"Reference of 73387-52-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 73387-52-7, name is 5-(4-Bromophenyl)-1-methyl-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3941\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Share a compound : 73387-52-7\" \/>\n<meta property=\"og:description\" content=\"Reference of 73387-52-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 73387-52-7, name is 5-(4-Bromophenyl)-1-methyl-1H-pyrazole, This compound has unique chemical properties. 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The synthetic route is as follows.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3941#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=3941\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3941#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Share a compound : 73387-52-7\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Share a compound : 73387-52-7","description":"Reference of 73387-52-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 73387-52-7, name is 5-(4-Bromophenyl)-1-methyl-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=3941","og_locale":"en_US","og_type":"article","og_title":"Share a compound : 73387-52-7","og_description":"Reference of 73387-52-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 73387-52-7, name is 5-(4-Bromophenyl)-1-methyl-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows.","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=3941","og_site_name":"pyrazoles-derivatives","article_published_time":"2021-05-10T19:57:25+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=3941","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=3941","name":"Share a compound : 73387-52-7","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2021-05-10T19:57:25+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Reference of 73387-52-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 73387-52-7, name is 5-(4-Bromophenyl)-1-methyl-1H-pyrazole, This compound has unique chemical properties. 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