{"id":3921,"date":"2021-05-10T04:38:55","date_gmt":"2021-05-09T20:38:55","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3921"},"modified":"2021-05-10T04:38:55","modified_gmt":"2021-05-09T20:38:55","slug":"extended-knowledge-of-4-1h-pyrazol-1-ylbenzonitrile","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3921","title":{"rendered":"Extended knowledge of 4-(1H-Pyrazol-1-yl)benzonitrile"},"content":{"rendered":"

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 25699-83-6 as follows. Product Details of 25699-83-6<\/a><\/p>\n

Into a 50-mL 3-necked round-bottom flask purged and maintained with an inert atmosphere of nitrogen, was placed tetrahydrofuran (15 mL). This was followed by dropwise addition of a 4-(1H-pyrazol-1-yl)benzonitrile (250 mg, 1.48 mmol, 1.00 equiv) in tetrahydrofuran (5 mL) with stirring at 0 C. To this was added LiAlH4 (337 mg, 8.87 mmol, 6.00 equiv). The resulting solution was stirred for 3 h at room temperature. The reaction was then quenched by the addition of NaOH (15%, aq). The resulting solution was extracted with 3*50 mL of dichloromethane and the organic layers were combined, dried over anhydrous sodium sulfate, and concentrated under vacuum. The product was obtained as 0.251 mg of a white crude solid.<\/p>\n

According to the analysis of related databases, 25699-83-6, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 25699-83-6, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[468,131],"tags":[126],"class_list":["post-3921","post","type-post","status-publish","format-standard","hentry","category-25699-83-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nExtended knowledge of 4-(1H-Pyrazol-1-yl)benzonitrile<\/title>\n<meta name=\"description\" content=\"In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 25699-83-6 as follows. 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