{"id":3893,"date":"2021-05-08T04:09:58","date_gmt":"2021-05-07T20:09:58","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3893"},"modified":"2021-05-08T04:09:58","modified_gmt":"2021-05-07T20:09:58","slug":"the-important-role-of-5-chloro-1-methyl-4-nitro-1h-pyrazole","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3893","title":{"rendered":"The important role of 5-Chloro-1-methyl-4-nitro-1H-pyrazole"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 42098-25-9, name is 5-Chloro-1-methyl-4-nitro-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 42098-25-9, Computed Properties of C4H4ClN3O2<\/a><\/p>\n

a mixture of (Z)-2,3,6,7-tetrahydro-1H-azepine hydrochloride (32.3 g; 0.24 mol), 5-chloro-1-methyl-4-nitro-1H-pyrazole (37.2 g; 0.23 mol), potassium fluoride (56.24 g; 0.96 mol), and diisopropylethylamine (64 ml; 0.362 mol) in anhydrous DMSO (650 ml) was heated at 75 C for 21 h. On cooling, the mixture was poured into water (1,500 ml), extracted with ethyl acetate (4 \u00d7 500 ml), and the combined organics washed with water (2 \u00d7 400 ml) and brine (300 ml) then dried (MgSO4). The solvent was removed under reduced pressure to afford (Z)-1-(1-methyl-4-nitro-1H-pyrazol-5-yl)-2,3,6,7-tetrahydro-1H-azepine as a light brown solid (50.74 g; 99%). 1H-NMR (400 MHz, CDCl3) delta 8.00 (s, 1H), 5.95-5.85 (m, 2H), 3.80(s, 3H), 3.30-3.20 (m, 4H), 2.45-2.35 (m, 4H). LC-MS (ESI m\/z): 223.1 [M + H+].<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Chloro-1-methyl-4-nitro-1H-pyrazole, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Chloro-1-methyl-4-nitro-1H-pyrazole, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[256,131],"tags":[126],"class_list":["post-3893","post","type-post","status-publish","format-standard","hentry","category-42098-25-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of 5-Chloro-1-methyl-4-nitro-1H-pyrazole<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 42098-25-9, name is 5-Chloro-1-methyl-4-nitro-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 42098-25-9, Computed Properties of C4H4ClN3O2\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3893\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The important role of 5-Chloro-1-methyl-4-nitro-1H-pyrazole\" \/>\n<meta property=\"og:description\" content=\"Adding a certain compound to certain chemical reactions, such as: 42098-25-9, name is 5-Chloro-1-methyl-4-nitro-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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