{"id":3860,"date":"2021-05-07T03:18:34","date_gmt":"2021-05-06T19:18:34","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3860"},"modified":"2021-05-07T03:18:34","modified_gmt":"2021-05-06T19:18:34","slug":"a-new-synthetic-route-of-ethyl-5-amino-1h-pyrazole-4-carboxylate","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3860","title":{"rendered":"A new synthetic route of Ethyl 5-amino-1H-pyrazole-4-carboxylate"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 1260243-04-6, name is Ethyl 5-amino-1H-pyrazole-4-carboxylate, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1260243-04-6, SDS of cas: 1260243-04-6<\/a><\/p>\n

To a mixture of ethyl 3-amino-1H-pyrazole-4-carboxylate (29) (30.0 g, 193 mmol) and ethyl 3-ethoxy-2-propenoate (cis- and trans-mixture, 41.9 mL, 290 mmol) in DMF(387 mL) was added cesium carbonate (113 g, 348 mmol). Themixture was stirred at 100C for 2 h, diluted with water andthen acidified to pH ca. 5 with AcOH. The resulting solid wasfiltered by filtration, washed with water and dried to afford 30(36.4 g, 176 mmol, 91%) as a beige solid. 1H-NMR (300 MHz,DMSO-d6) delta: 1.28 (3H, t, J=7.1 Hz), 4.28 (2H, q, J=7.1 Hz),6.15 (1H, d, J=7.9 Hz), 8.13 (1H, s), 8.57 (1H, d, J=7.9 Hz),11.73 (1H, br s).<\/p>\n

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"excerpt":{"rendered":"

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[213,131],"tags":[126],"class_list":["post-3860","post","type-post","status-publish","format-standard","hentry","category-1260243-04-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nA new synthetic route of Ethyl 5-amino-1H-pyrazole-4-carboxylate<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 1260243-04-6, name is Ethyl 5-amino-1H-pyrazole-4-carboxylate, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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