{"id":3848,"date":"2021-05-07T03:17:51","date_gmt":"2021-05-06T19:17:51","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3848"},"modified":"2021-05-07T03:17:51","modified_gmt":"2021-05-06T19:17:51","slug":"share-a-compound-methyl-5-methyl-1h-pyrazole-3-carboxylate","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3848","title":{"rendered":"Share a compound : Methyl 5-methyl-1H-pyrazole-3-carboxylate"},"content":{"rendered":"<p>Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 25016-17-5, name is Methyl 5-methyl-1H-pyrazole-3-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., <a href=\"https:\/\/www.ambeed.com\/products\/25016-17-5.html\">Recommanded Product: 25016-17-5<\/a><\/p>\n<p>5-methyl-1- (pyrimidin-2-yl-methyl)lH-pyrazole-3-carboxylate (Scheme C-1)5-methyl -1H- pyrazole-3-carboxylate (4.60 g of the) in90mLN, N- dimethylformamideAmine solution and potassium carbonate (10.88g) and themixture is stirred at room temperature for 15 minutes.Then, 2- (chloromethyl) pyrimidine hydrochloride (6.49 gof), and the reaction mixture was heated at reflux18 hours, poured into 300mL water and extracted with ethylacetate. The organic phase was dried with sodium sulfate,Filtered and concentrated under reduced pressure. By columnchromatography on silica gel with cyclohexane \/ ethyl acetate (1: 9)The crude product was purified as eluent. 0.96g3- givemethyl-1- (pyrimidin-2-ylmethyl) lH-Pyrazole-5-carboxylate and 3.85g of the titlecompoun<\/p>\n<p>According to the analysis of related databases, 25016-17-5, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>According to the analysis of related databases, 25016-17-5, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[470,131],"tags":[126],"class_list":["post-3848","post","type-post","status-publish","format-standard","hentry","category-25016-17-5","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Share a compound : Methyl 5-methyl-1H-pyrazole-3-carboxylate<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 25016-17-5, name is Methyl 5-methyl-1H-pyrazole-3-carboxylate, This compound has unique chemical properties. 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The synthetic route is as follows., Recommanded Product: 25016-17-5","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=3848","og_locale":"en_US","og_type":"article","og_title":"Share a compound : Methyl 5-methyl-1H-pyrazole-3-carboxylate","og_description":"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 25016-17-5, name is Methyl 5-methyl-1H-pyrazole-3-carboxylate, This compound has unique chemical properties. 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