{"id":3787,"date":"2021-05-06T04:34:47","date_gmt":"2021-05-05T20:34:47","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3787"},"modified":"2021-05-06T04:34:47","modified_gmt":"2021-05-05T20:34:47","slug":"the-origin-of-a-common-compound-about-4-amino-1-methyl-3-n-propyl-1h-pyrazole-5-carboxamide-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3787","title":{"rendered":"The origin of a common compound about 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide"},"content":{"rendered":"

Electric Literature of 139756-02-8<\/a>, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 139756-02-8, name is 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.<\/p>\n

In a typical procedure, a solution of aromatic aldehyde i.e. 2,4,5-trimethoxybenzaldehyde (0.196g, 1eq.) and 4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide (0.191g, 1.05eq) in DMSO:H2O (1:1) add K2S2O8 (0.810 g, 3 eq.) was taken in a sealed reaction tube and the reaction mixture was irradiated under microwave conditions for 3min with a power of 350 Watts at 100C. After completion, the reaction mass was diluted with EtOAc (20mL) and added water (30mL). Separated the organic layer and extracted with EtOAc (2\u00d710 mL). The combined organic layer was then washed with brine solution, concentrated under vacuum and purified on silica-gel (100-200 mesh) column chromatography, affording white solid 1-methyl-3-propyl-5-(2,4,5-trimethoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one i.e.compound 3j in (0.351g) 98% yield.<\/p>\n

The synthetic route of 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[157,131],"tags":[126],"class_list":["post-3787","post","type-post","status-publish","format-standard","hentry","category-139756-02-8","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe origin of a common compound about 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide<\/title>\n<meta name=\"description\" content=\"Electric Literature of 139756-02-8, In the next few decades, the world population will flourish. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The origin of a common compound about 4-Amino-1-methyl-3-N-propyl-1H-pyrazole-5-carboxamide","description":"Electric Literature of 139756-02-8, In the next few decades, the world population will flourish. 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