{"id":3785,"date":"2021-05-06T04:34:47","date_gmt":"2021-05-05T20:34:47","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3785"},"modified":"2021-05-06T04:34:47","modified_gmt":"2021-05-05T20:34:47","slug":"the-important-role-of-3-tert-butylpyrazole-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3785","title":{"rendered":"The important role of 3-(tert-Butyl)pyrazole"},"content":{"rendered":"<p>Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 15802-80-9, name is 3-(tert-Butyl)pyrazole, This compound has unique chemical properties. The synthetic route is as follows., <a href=\"https:\/\/www.ambeed.com\/products\/15802-80-9.html\">Safety of 3-(tert-Butyl)pyrazole<\/a><\/p>\n<p>Reference Example 274 To a mixture of3-tert-butyl-lH-pyrazole (3.72 g), 2-chloro-5- (trifluoromethyl) pyridine (5.45 g) and N- methylpyrrolidone (18.6 ml) was added sodium hydroxide (1.80 g) while stirring the mixture at room temperature. After allowing reaction as it was for 8 hours, water (38 ml) and 6N hydrochloric acid (80 ml) were added and the mixture was extracted with ethyl acetate. The extract was washed with water and concentrated under reduced pressure. The residue was subjected to silica gel column chromatography, and eluted with hexane and then with toluene to give2- (3-tert-butyl-lH-pyrazol-1-yl)-5-(trifluoromethyl) pyridine (7.04 g, yield87%) as a colorless oil. H-NMR (CDC13) 5 : 1.37 (9H, s), 6.37 (lH, d, J=2.6 Hz), 7.97 (1H, dd, J=8.7, 2.1 Hz), 8.08 (1H, d, J=8.7 Hz), 8.46 (1H, d, J=2.7 Hz), 8.6-8. 7 (1H, m).<\/p>\n<p>According to the analysis of related databases, 15802-80-9, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>According to the analysis of related databases, 15802-80-9, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[398,131],"tags":[126],"class_list":["post-3785","post","type-post","status-publish","format-standard","hentry","category-15802-80-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The important role of 3-(tert-Butyl)pyrazole<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 15802-80-9, name is 3-(tert-Butyl)pyrazole, This compound has unique chemical properties. 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