{"id":3720,"date":"2021-04-29T04:42:03","date_gmt":"2021-04-28T20:42:03","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3720"},"modified":"2021-04-29T04:42:03","modified_gmt":"2021-04-28T20:42:03","slug":"research-on-new-synthetic-routes-about-5-iodo-1-methyl-1h-pyrazole","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3720","title":{"rendered":"Research on new synthetic routes about 5-Iodo-1-methyl-1H-pyrazole"},"content":{"rendered":"

Synthetic Route of 34091-51-5<\/a>,Some common heterocyclic compound, 34091-51-5, name is 5-Iodo-1-methyl-1H-pyrazole, molecular formula is C4H5IN2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.<\/p>\n

A deoxygenated mixture of 2- (4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolan-2-yl) -1H-indole (100 mg, 0.411 mmol) , 5-iodo-1-methyl-1H-pyrazole (860 mg, 0.411 mmol) , bis (triphenylphosphine) palladium (II) chloride (14 mg, 0.021 mmol) , and aqueous sodium carbonate solution (0.620 mL, 2M) in dioxane (2 mL) was heated under microwave irradiation at 120 for 30 minutes. The reaction mixture was cooled, diluted with EtOAc (5 mL) , filtered and concentrated. The residue was purified by column chromatography on silica gel (0-50EtOAc in hexanes) to afford the title compound. MS: m\/z 198.1 (M + 1) .<\/p>\n

The synthetic route of 34091-51-5 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 34091-51-5 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[273,131],"tags":[127],"class_list":["post-3720","post","type-post","status-publish","format-standard","hentry","category-34091-51-5","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nResearch on new synthetic routes about 5-Iodo-1-methyl-1H-pyrazole<\/title>\n<meta name=\"description\" content=\"Synthetic Route of 34091-51-5,Some common heterocyclic compound, 34091-51-5, name is 5-Iodo-1-methyl-1H-pyrazole, molecular formula is C4H5IN2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=3720\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research on new synthetic routes about 5-Iodo-1-methyl-1H-pyrazole\" \/>\n<meta property=\"og:description\" content=\"Synthetic Route of 34091-51-5,Some common heterocyclic compound, 34091-51-5, name is 5-Iodo-1-methyl-1H-pyrazole, molecular formula is C4H5IN2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.\" \/>\n<meta property=\"og:url\" content=\"http:\/\/www.pyrazoles-derivatives.com\/?p=3720\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-04-28T20:42:03+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=3720\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=3720\",\"name\":\"Research on new synthetic routes about 5-Iodo-1-methyl-1H-pyrazole\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-04-28T20:42:03+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Synthetic Route of 34091-51-5,Some common heterocyclic compound, 34091-51-5, name is 5-Iodo-1-methyl-1H-pyrazole, molecular formula is C4H5IN2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.\",\"breadcrumb\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=3720#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\/\/www.pyrazoles-derivatives.com\/?p=3720\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=3720#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research on new synthetic routes about 5-Iodo-1-methyl-1H-pyrazole\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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