{"id":3708,"date":"2021-04-28T07:50:31","date_gmt":"2021-04-27T23:50:31","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3708"},"modified":"2021-04-28T07:50:31","modified_gmt":"2021-04-27T23:50:31","slug":"application-of-3-bromo-1-methyl-1h-pyrazole","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3708","title":{"rendered":"Application of 3-Bromo-1-methyl-1H-pyrazole"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 151049-87-5, name is 3-Bromo-1-methyl-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows., Formula: C4H5BrN2<\/a><\/p>\n

To a mixture of 3-bromo-1-methylpyrazole (0.91 g), toluene (18 mL), ethanol (3.0 mL) and water (3.0 mL) were added (4-(hydroxymethyl)phenyl)boronic acid (1.1 g), sodium carbonate (0.60 g) and dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium (0.52 g) at room temperature, and the mixture was stirred under an argon atmosphere at 110 C. overnight. The reaction mixture was filtered, and the filtrate was diluted with ethyl acetate, washed with water and saturated brine and dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure and the residue was purified by silica gel column chromatography (ethyl acetate\/hexane) and triturated with ethyl acetate and hexane to give the title compound (1.1 g). MS: [M+H]+ 189.1<\/p>\n

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 151049-87-5.<\/p>\n","protected":false},"excerpt":{"rendered":"

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 151049-87-5.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[331,131],"tags":[126],"class_list":["post-3708","post","type-post","status-publish","format-standard","hentry","category-151049-87-5","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nApplication of 3-Bromo-1-methyl-1H-pyrazole<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 151049-87-5, name is 3-Bromo-1-methyl-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows., Formula: C4H5BrN2\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3708\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Application of 3-Bromo-1-methyl-1H-pyrazole\" \/>\n<meta property=\"og:description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 151049-87-5, name is 3-Bromo-1-methyl-1H-pyrazole, This compound has unique chemical properties. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Application of 3-Bromo-1-methyl-1H-pyrazole","description":"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 151049-87-5, name is 3-Bromo-1-methyl-1H-pyrazole, This compound has unique chemical properties. 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