{"id":3689,"date":"2021-04-28T07:49:48","date_gmt":"2021-04-27T23:49:48","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3689"},"modified":"2021-04-28T07:49:48","modified_gmt":"2021-04-27T23:49:48","slug":"share-a-compound-methyl-4-nitro-1h-pyrazole-3-carboxylate","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3689","title":{"rendered":"Share a compound : Methyl 4-nitro-1H-pyrazole-3-carboxylate"},"content":{"rendered":"

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 138786-86-4, name is Methyl 4-nitro-1H-pyrazole-3-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Safety of Methyl 4-nitro-1H-pyrazole-3-carboxylate<\/a><\/p>\n

Reference Example 20 Methyl 1-methyl-4-nitro-1H-pyrazole-5-carboxylate A mixture of methyl 4-nitro-1H-pyrazole-3-carboxylate obtained in Reference Example 18 (2.0 g, 11.7 mmol), methyl iodide (2.0 g, 14.0 mmol), potassium carbonate (1.62 g, 11.7 mmol) and acetone (60 mL) was stirred at 30 C. for 5 hr. The mixture was diluted with water, and extracted with chloroform. The extract was dried over anhydrous sodium sulfate, and the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (hexane-ethyl acetate 4:1-1:1) to give the title compound, methyl 1-methyl-4-nitro-1H-pyrazole-3-carboxylate (Rf value 0.43) (0.95 g, yield 44%) and the title compound, methyl 1-methyl-4-nitro-1H-pyrazole-5-carboxylate (Rf value 0.71) (0.61 g, yield 28%).<\/p>\n

The synthetic route of 138786-86-4 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 138786-86-4 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[271,131],"tags":[126],"class_list":["post-3689","post","type-post","status-publish","format-standard","hentry","category-138786-86-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nShare a compound : Methyl 4-nitro-1H-pyrazole-3-carboxylate<\/title>\n<meta name=\"description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 138786-86-4, name is Methyl 4-nitro-1H-pyrazole-3-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. 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