{"id":3674,"date":"2021-04-27T07:53:50","date_gmt":"2021-04-26T23:53:50","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3674"},"modified":"2021-04-27T07:53:50","modified_gmt":"2021-04-26T23:53:50","slug":"the-important-role-of-ethyl-3-difluoromethyl-1-methyl-1h-pyrazole-4-carboxylate","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3674","title":{"rendered":"The important role of Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate"},"content":{"rendered":"

141573-95-7, name is Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. SDS of cas: 141573-95-7<\/a><\/p>\n

To the toluene layer was added 25% caustic soda solution159 g (0.994 mole) of the compound were added thereto, and the mixture was heated to 65 DEG C and stirred for 45 minutes. The aqueous layer was separated, and 54 g of water and 160.2 g (1.54 mole) of 35% hydrochloric acid were added to the toluene layer, followed by stirring at 85 for 15 minutes. After cooling to room temperature the resulting crystals were filtered, washed with 180 g of water and dried in vacuo at 60 & lt; RTI ID = 0.0 & gt;To obtain 155.8 g (yield 98%) of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid.<\/p>\n

The synthetic route of 141573-95-7 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 141573-95-7 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[187,131],"tags":[127],"class_list":["post-3674","post","type-post","status-publish","format-standard","hentry","category-141573-95-7","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nThe important role of Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate<\/title>\n<meta name=\"description\" content=\"141573-95-7, name is Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 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