{"id":3612,"date":"2021-04-25T06:34:44","date_gmt":"2021-04-24T22:34:44","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3612"},"modified":"2021-04-25T06:34:44","modified_gmt":"2021-04-24T22:34:44","slug":"sources-of-common-compounds-diethyl-35-pyrazoledicarboxylate-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3612","title":{"rendered":"Sources of common compounds: Diethyl 3,5-pyrazoledicarboxylate"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 37687-24-4, name is Diethyl 3,5-pyrazoledicarboxylate, A new synthetic method of this compound is introduced below., Recommanded Product: 37687-24-4<\/a><\/p>\n

A mixture of diethyl 1H-pyrazole-3,5-dicarboxylate (5.20 g, 24.5 mmol), 2-chloro-1-(3-chloro-4-methylphenyl)ethan-1-one (4.98 g, 24.5 mmol), potassium carbonate (3.73 g, 27.0 mmol) and water (3 drops) in acetone (100 ml) was stirred at RT overnight. The solids were then filtered off, and the filtrate was concentrated under reduced pressure. The residue was partitioned between dichloromethane and water. The layers were separated, and the organic layer was washed with water and brine, dried over sodium sulfate and filtered. The filtrate was concentrated under re- duced pressure to afford the crude title compound which was directly used in the next step with- out further purification. Yield: 7.99 g (83% of theory, 97% purity). LC\/MS [Method 34]: Rt = 1.39 min; MS (ESIpos): m\/z = 379\/381 [M+H]+.<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[291,131],"tags":[127],"class_list":["post-3612","post","type-post","status-publish","format-standard","hentry","category-37687-24-4","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nSources of common compounds: Diethyl 3,5-pyrazoledicarboxylate<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 37687-24-4, name is Diethyl 3,5-pyrazoledicarboxylate, A new synthetic method of this compound is introduced below., Recommanded Product: 37687-24-4\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3612\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sources of common compounds: Diethyl 3,5-pyrazoledicarboxylate\" \/>\n<meta property=\"og:description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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