{"id":3566,"date":"2021-04-23T06:34:19","date_gmt":"2021-04-22T22:34:19","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3566"},"modified":"2021-04-23T06:34:19","modified_gmt":"2021-04-22T22:34:19","slug":"new-learning-discoveries-about-ethyl-4-nitro-1h-pyrazole-3-carboxylate","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3566","title":{"rendered":"New learning discoveries about Ethyl 4-nitro-1H-pyrazole-3-carboxylate"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 55864-87-4, name is Ethyl 4-nitro-1H-pyrazole-3-carboxylate, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 55864-87-4, Formula: C6H7N3O4<\/a><\/p>\n

To a mixture of compound A32 (12.4 g, 66.9 mmol, 1 eq) and K2CO3 (23.1 g, 167 mmol, 2.5 eq) in MeCN (120 mL) was added Dl-1 (28.5 g, 167 mmol, 16.4 mL, 2.5 eq) and the resulting mixture was heated to 60-70C for 16 hours to afford a white mixture. TLC showed two new spots. The mixture was partitioned between EtOAc (100 mL) and H20 (100 mL). The aqueous phase was extracted with EtOAc (100 mL x 2). The combined organic extract was dried over anhydrous Na2S04, filtered and concentrated under reduced pressure to give crude product. The crude product was purified by combi flash (PE\/EtOAc = 1\/0 to 4\/1 to 3\/1) to afford compound A33 (9.5 g, 62.4% yield) as a yellow oil.<\/p>\n

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"excerpt":{"rendered":"

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[258,131],"tags":[126],"class_list":["post-3566","post","type-post","status-publish","format-standard","hentry","category-55864-87-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nNew learning discoveries about Ethyl 4-nitro-1H-pyrazole-3-carboxylate<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 55864-87-4, name is Ethyl 4-nitro-1H-pyrazole-3-carboxylate, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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