{"id":3551,"date":"2021-04-21T09:28:54","date_gmt":"2021-04-21T01:28:54","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3551"},"modified":"2021-04-21T09:28:54","modified_gmt":"2021-04-21T01:28:54","slug":"the-origin-of-a-common-compound-about-1h-pyrazole-4-carbonitrile","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3551","title":{"rendered":"The origin of a common compound about 1H-Pyrazole-4-carbonitrile"},"content":{"rendered":"

Application of 31108-57-3<\/a>, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 31108-57-3 as follows.<\/p>\n

General procedure: Prepared according General Procedure B from compound All (25 mg, 0.057 mmol) and 5- chlorotriazole (106 mg, 1.14 mmol), with purification by reverse phase preparative HPLC to provide compound 13 as a white solid (16.8 mg, 65%): mp 141-142 C; 1HNMR (500 MHz, CDC13) delta 7.85 (s, IH), 7.80 (s, IH), 4.95 (dd, J= 62.5, 17.5 Hz, 2H), 3.47 (dd, J= 10.0 Hz, IH), 3.37 (dd, J = 10.0 Hz, IH), 3.28 (s, 3H), 2.60 (t, J = 9.0 Hz, IH), 2.23-2.20 (m, IH), 2.05-2.01 (m, 2H), 1.76-1.69 (m, 4H), 1.63-1.49 (m, 7H), 1.47-1.10 (m, 10H), 0.99-0.97 (m, 1H), 0.87-0.85 (m, 1H), 0.69 (s, 3H) ppm; ESI MS m\/z 436 [M+H-H20]+ .<\/p>\n

According to the analysis of related databases, 31108-57-3, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 31108-57-3, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[326,131],"tags":[145],"class_list":["post-3551","post","type-post","status-publish","format-standard","hentry","category-31108-57-3","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"\nThe origin of a common compound about 1H-Pyrazole-4-carbonitrile<\/title>\n<meta name=\"description\" content=\"Application of 31108-57-3, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 31108-57-3 as follows.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=3551\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The origin of a common compound about 1H-Pyrazole-4-carbonitrile\" \/>\n<meta property=\"og:description\" content=\"Application of 31108-57-3, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. 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