{"id":3542,"date":"2021-04-21T09:28:12","date_gmt":"2021-04-21T01:28:12","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3542"},"modified":"2021-04-21T09:28:12","modified_gmt":"2021-04-21T01:28:12","slug":"brief-introduction-of-5-methyl-1h-pyrazol-3-amine","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3542","title":{"rendered":"Brief introduction of 5-Methyl-1H-pyrazol-3-amine"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 31230-17-8, name is 5-Methyl-1H-pyrazol-3-amine, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 5-Methyl-1H-pyrazol-3-amine<\/a><\/p>\n

Intermediate 14; 2-Chloro-5 -methyl-N-(5 -methyl- lH-pyrazol-3-yl)pyrimidin-4-amine2,4-Dichloro-5-methylpyrimidine (2.395 g, 14.69 mmol), 5 -methyl- lH-pyrazo 1-3 -amine (1.710 g,17.61 mmol), and DIPEA (3.80 g, 29.39 mmol) in ethanol (20 ml) was heated at 6O0C over the weekend. LCMS indicated complete reaction. Solvent was removed under reduced pressure and the residue was purified by ISCO (5percentMeOH\/0.5percent NH4OH in CH2Cl2. 2.5g (76percent) of the title compound was isolated.1H NMR (400 MHz, DMSO-d6) delta ppm 12.17 (s, 1 H) 9.30 (s, 1 H) 7.97 (s, 1 H) 6.37 (s, 1 H) 2.25 (s, 3 H) 2.13 (s, 3 H). LCMS: 224 [M+H]+.<\/p>\n

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 31230-17-8.<\/p>\n","protected":false},"excerpt":{"rendered":"

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 31230-17-8.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[207,131],"tags":[145],"class_list":["post-3542","post","type-post","status-publish","format-standard","hentry","category-31230-17-8","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"\nBrief introduction of 5-Methyl-1H-pyrazol-3-amine<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 31230-17-8, name is 5-Methyl-1H-pyrazol-3-amine, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 5-Methyl-1H-pyrazol-3-amine\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3542\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brief introduction of 5-Methyl-1H-pyrazol-3-amine\" \/>\n<meta property=\"og:description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 31230-17-8, name is 5-Methyl-1H-pyrazol-3-amine, This compound has unique chemical properties. 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