{"id":3504,"date":"2021-04-20T08:49:40","date_gmt":"2021-04-20T00:49:40","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3504"},"modified":"2021-04-20T08:49:40","modified_gmt":"2021-04-20T00:49:40","slug":"introduction-of-a-new-synthetic-route-about-diethyl-1h-pyrazole-34-dicarboxylate","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3504","title":{"rendered":"Introduction of a new synthetic route about Diethyl 1H-pyrazole-3,4-dicarboxylate"},"content":{"rendered":"

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 37687-26-6, name is Diethyl 1H-pyrazole-3,4-dicarboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Product Details of 37687-26-6<\/a><\/p>\n

To a stirred solution of 104B (19 g, 90 mmol) in DMF (50 mL) was added NIS (30.2 g, 134 mmol) and the reaction mixture was stirred for 16 h at 115 C. LCMS indicated the completion of the reaction. DMF was evaporated, the crude was dissolved in EtOAc, washed with water, sodium thiosulfate solution, dried, filtered and evaporated under vacuum to furnish crude product, which was purified by ISCO using EtOAc and hexane system. Fractions collected at 18-20% EtOAc in hexane were evaporated to get 104C (12.5 g, 37.0 mmol, 41.3% yield). MS(ES): m\/z=338 [M+H]+; 1H NMR (400 MHz, DMSO-d6) delta ppm 14.25 (bs, 1H), 4.27 (m, 4H), 1.26 (m, 6H).<\/p>\n

The synthetic route of 37687-26-6 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 37687-26-6 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[542,131],"tags":[127],"class_list":["post-3504","post","type-post","status-publish","format-standard","hentry","category-37687-26-6","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nIntroduction of a new synthetic route about Diethyl 1H-pyrazole-3,4-dicarboxylate<\/title>\n<meta name=\"description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 37687-26-6, name is Diethyl 1H-pyrazole-3,4-dicarboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Product Details of 37687-26-6\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=3504\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Introduction of a new synthetic route about Diethyl 1H-pyrazole-3,4-dicarboxylate\" \/>\n<meta property=\"og:description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 37687-26-6, name is Diethyl 1H-pyrazole-3,4-dicarboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. 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As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 37687-26-6, name is Diethyl 1H-pyrazole-3,4-dicarboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. 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