{"id":3496,"date":"2021-04-20T08:49:40","date_gmt":"2021-04-20T00:49:40","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3496"},"modified":"2021-04-20T08:49:40","modified_gmt":"2021-04-20T00:49:40","slug":"new-learning-discoveries-about-1-4-chloromethylphenyl-1h-pyrazole","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3496","title":{"rendered":"New learning discoveries about 1-(4-(Chloromethyl)phenyl)-1H-pyrazole"},"content":{"rendered":"

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 143426-52-2 as follows. Recommanded Product: 1-(4-(Chloromethyl)phenyl)-1H-pyrazole<\/a><\/p>\n

To a mixture of methyl 2-amino-3, 4-dimethyl-5- (4, 4, 5, 5- tetramethyl-1, 3, 2-dioxaborolan-2-yl) benzoate (0.69 g) , l-(4- (chloromethyl) phenyl) -lH-pyrazole (0.46 g) , 2 M aqueous sodium carbonate solution (2.26 mL) and DME (20 mL) was added (1,1- bis (diphenylphosphino) ferrocene) dichloropalladium ( II) (1707) dichloromethane adduct (0.09 g) under an argon atmosphere and the mixture was stirred at 80C overnight. The reaction mixture was dried over anhydrous sodium sulfate and (1708) concentrated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate\/hexane) to give the title compound (0.65 g) . (1709) MS: [M+H]+ 336.1<\/p>\n

According to the analysis of related databases, 143426-52-2, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 143426-52-2, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[223,131],"tags":[126],"class_list":["post-3496","post","type-post","status-publish","format-standard","hentry","category-143426-52-2","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nNew learning discoveries about 1-(4-(Chloromethyl)phenyl)-1H-pyrazole<\/title>\n<meta name=\"description\" content=\"In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 143426-52-2 as follows. 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