{"id":3483,"date":"2021-04-19T06:35:10","date_gmt":"2021-04-18T22:35:10","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3483"},"modified":"2021-04-19T06:35:10","modified_gmt":"2021-04-18T22:35:10","slug":"some-tips-on-5-bromo-1-methyl-1h-pyrazol-3-amine","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3483","title":{"rendered":"Some tips on 5-Bromo-1-methyl-1H-pyrazol-3-amine"},"content":{"rendered":"

Application of 89088-55-1<\/a>, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 89088-55-1 as follows.<\/p>\n

To a solution of compound 32-2 (70 mg, 187.4 umol) and DIEA (36 mg, 281.1 umol, 49.1 uL) in DCM (3.0 mL) at -20C was added triphosgene (18 mg, 61.8 umol). The mixture was stirred at -20C for 1 h. Then a solution of 5-bromo-l-methyl-lH-pyrazol-3-amine (33 mg, 187.4 umol) in DCM (1.0 mL) was added. The resulting mixture was stirred at 25C for 12 h and concentrated to get a crude residue which was purified by prep-TLC (Si02) to afford compound 32-3 (90 mg).<\/p>\n

According to the analysis of related databases, 89088-55-1, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 89088-55-1, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[379,131],"tags":[126],"class_list":["post-3483","post","type-post","status-publish","format-standard","hentry","category-89088-55-1","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nSome tips on 5-Bromo-1-methyl-1H-pyrazol-3-amine<\/title>\n<meta name=\"description\" content=\"Application of 89088-55-1, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 89088-55-1 as follows.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3483\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Some tips on 5-Bromo-1-methyl-1H-pyrazol-3-amine\" \/>\n<meta property=\"og:description\" content=\"Application of 89088-55-1, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. 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