{"id":3367,"date":"2021-04-13T00:00:00","date_gmt":"2021-04-12T16:00:00","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3367"},"modified":"2021-04-13T00:00:00","modified_gmt":"2021-04-12T16:00:00","slug":"continuously-updated-synthesis-method-about-4-amino-1-methyl-1h-pyrazole-3-carboxamide","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3367","title":{"rendered":"Continuously updated synthesis method about 4-Amino-1-methyl-1H-pyrazole-3-carboxamide"},"content":{"rendered":"<p><a href=\"https:\/\/www.ambeed.com\/products\/3920-40-9.html\">Related Products of 3920-40-9<\/a>, The chemical industry reduces the impact on the environment during synthesis 3920-40-9, name is 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, I believe this compound will play a more active role in future production and life.<\/p>\n<p>A mixture of 2-bromothiazole-4-carboxylic acid (891 mg), 4-amino-1-methyl-1H-pyrazole-3-carboxamide (600 mg) and HATU (1.95 g) in DMF (5 ml) and ethyldiisopropylamine (1.5 ml) is stirred at room temperature for 20 h and then poured into ice-water. The precipitated solid is filtered off, washed twice with water and three times each with diethyl ether and ethyl acetate and dried in vacuo (889 mg).C9H8BrN5O2S (329.0), LC-MS (ZQ): Rt=0.87, m\/z=330 [M+H]+. 1H-NMR (300 MHz, D6-DMSO): 3.88 (s, 3H), 7.45 (br. s., 1H), 7.70 (br. s., 1H), 8.31 (s, 1H), 8.41 (s, 1H), 11.0 (s, 1H).<\/p>\n<p>In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[526,131],"tags":[126],"class_list":["post-3367","post","type-post","status-publish","format-standard","hentry","category-3920-40-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Continuously updated synthesis method about 4-Amino-1-methyl-1H-pyrazole-3-carboxamide<\/title>\n<meta name=\"description\" content=\"Related Products of 3920-40-9, The chemical industry reduces the impact on the environment during synthesis 3920-40-9, name is 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, I believe this compound will play a more active role in future production and life.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3367\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Continuously updated synthesis method about 4-Amino-1-methyl-1H-pyrazole-3-carboxamide\" \/>\n<meta property=\"og:description\" content=\"Related Products of 3920-40-9, The chemical industry reduces the impact on the environment during synthesis 3920-40-9, name is 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, I believe this compound will play a more active role in future production and life.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3367\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-04-12T16:00:00+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3367\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3367\",\"name\":\"Continuously updated synthesis method about 4-Amino-1-methyl-1H-pyrazole-3-carboxamide\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-04-12T16:00:00+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Related Products of 3920-40-9, The chemical industry reduces the impact on the environment during synthesis 3920-40-9, name is 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, I believe this compound will play a more active role in future production and life.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3367#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=3367\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3367#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Continuously updated synthesis method about 4-Amino-1-methyl-1H-pyrazole-3-carboxamide\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Continuously updated synthesis method about 4-Amino-1-methyl-1H-pyrazole-3-carboxamide","description":"Related Products of 3920-40-9, The chemical industry reduces the impact on the environment during synthesis 3920-40-9, name is 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, I believe this compound will play a more active role in future production and life.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=3367","og_locale":"en_US","og_type":"article","og_title":"Continuously updated synthesis method about 4-Amino-1-methyl-1H-pyrazole-3-carboxamide","og_description":"Related Products of 3920-40-9, The chemical industry reduces the impact on the environment during synthesis 3920-40-9, name is 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, I believe this compound will play a more active role in future production and life.","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=3367","og_site_name":"pyrazoles-derivatives","article_published_time":"2021-04-12T16:00:00+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=3367","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=3367","name":"Continuously updated synthesis method about 4-Amino-1-methyl-1H-pyrazole-3-carboxamide","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2021-04-12T16:00:00+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Related Products of 3920-40-9, The chemical industry reduces the impact on the environment during synthesis 3920-40-9, name is 4-Amino-1-methyl-1H-pyrazole-3-carboxamide, I believe this compound will play a more active role in future production and life.","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=3367#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=3367"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=3367#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Continuously updated synthesis method about 4-Amino-1-methyl-1H-pyrazole-3-carboxamide"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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