{"id":3340,"date":"2021-04-13T00:00:00","date_gmt":"2021-04-12T16:00:00","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3340"},"modified":"2021-04-13T00:00:00","modified_gmt":"2021-04-12T16:00:00","slug":"sources-of-common-compounds-ethyl-5-amino-1-4-fluorophenyl-1h-pyrazole-4-carboxylate","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3340","title":{"rendered":"Sources of common compounds: Ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 138907-68-3, name is Ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 138907-68-3<\/a><\/p>\n

Intermediate 9: 5-Amino-1-(4-fluorophenyl)-1 H-pyrazole-4-carboxylic acid. To a suspension of ethyl 5-amino-1-(4-fluorophenyl)-1 H-pyrazole-4-carboxylate (12.1g, 48.5mmol) in ethanol (250ml) was added a solution of lithium hydroxide(5.8g, 242mmol) in water (100ml). The mixture was stirred at reflux for 2.5hr. It was allowed to cool and concentrated to 50% of its volume before 5M hydrochloric acid(47ml) was added. After stirring for 15mins, the resulting white solid was filtered off and further 5M hydrochloric acid (3ml) was added. This was filtered and the combined solids were washed with water and diethyl ether and then dried under vacuum to give the title compound (10.27g).1 H NMR (400 MHz, DMSO-d6) deltappm 12.09 (br. s., 1 H) 7.67 (s, 1 H) 7.54 – 7.60 (m, 2H) 7.34 – 7.41 (m, 2 H) 6.29 (br. s., 2 H).LC-MS Retention Time 2.20mins, MH+ 222.<\/p>\n

According to the analysis of related databases, 138907-68-3, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 138907-68-3, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[523,131],"tags":[127],"class_list":["post-3340","post","type-post","status-publish","format-standard","hentry","category-138907-68-3","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nSources of common compounds: Ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 138907-68-3, name is Ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 138907-68-3\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3340\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sources of common compounds: Ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate\" \/>\n<meta property=\"og:description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 138907-68-3, name is Ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate, This compound has unique chemical properties. 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The synthetic route is as follows., Product Details of 138907-68-3","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=3340","og_locale":"en_US","og_type":"article","og_title":"Sources of common compounds: Ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate","og_description":"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 138907-68-3, name is Ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate, This compound has unique chemical properties. 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