{"id":3333,"date":"2021-04-12T00:00:00","date_gmt":"2021-04-11T16:00:00","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3333"},"modified":"2021-04-12T00:00:00","modified_gmt":"2021-04-11T16:00:00","slug":"the-important-role-of-1h-pyrazol-3-ylmethanamine-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3333","title":{"rendered":"The important role of (1H-Pyrazol-3-yl)methanamine"},"content":{"rendered":"

Reference of 37599-58-9<\/a>, A common heterocyclic compound, 37599-58-9, name is (1H-Pyrazol-3-yl)methanamine, molecular formula is C4H7N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.<\/p>\n

General procedure: Compound 1 (535 mg, 3.00 mmol, 1 equiv.)was dissolved in MeOH (3 mL). The corresponding amine(3.6 mmol) was added. The reaction mixture was stirred at RT for overnight. The solvent was removed under reduced pressure. The residue was purified by column chromatography(neutral Al2O3, EtOAc\/hexane) to give pure compound 2.<\/p>\n

The synthetic route of 37599-58-9 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 37599-58-9 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[522,131],"tags":[145],"class_list":["post-3333","post","type-post","status-publish","format-standard","hentry","category-37599-58-9","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"\nThe important role of (1H-Pyrazol-3-yl)methanamine<\/title>\n<meta name=\"description\" content=\"Reference of 37599-58-9, A common heterocyclic compound, 37599-58-9, name is (1H-Pyrazol-3-yl)methanamine, molecular formula is C4H7N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3333\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The important role of (1H-Pyrazol-3-yl)methanamine\" \/>\n<meta property=\"og:description\" content=\"Reference of 37599-58-9, A common heterocyclic compound, 37599-58-9, name is (1H-Pyrazol-3-yl)methanamine, molecular formula is C4H7N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3333\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-04-11T16:00:00+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3333\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3333\",\"name\":\"The important role of (1H-Pyrazol-3-yl)methanamine\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-04-11T16:00:00+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Reference of 37599-58-9, A common heterocyclic compound, 37599-58-9, name is (1H-Pyrazol-3-yl)methanamine, molecular formula is C4H7N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3333#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=3333\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=3333#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"The important role of (1H-Pyrazol-3-yl)methanamine\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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