{"id":3192,"date":"2021-04-08T00:00:00","date_gmt":"2021-04-07T16:00:00","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3192"},"modified":"2021-04-08T00:00:00","modified_gmt":"2021-04-07T16:00:00","slug":"simple-exploration-of-3-nitro-1h-pyrazole-1-ethanol","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3192","title":{"rendered":"Simple exploration of 3-Nitro-1H-pyrazole-1-ethanol"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 956951-01-2, name is 3-Nitro-1H-pyrazole-1-ethanol, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 3-Nitro-1H-pyrazole-1-ethanol<\/a><\/p>\n

To a stirred solution of compound 95 (4.0 g, 25.477 mmol) in CH2C12 (50 mL) was added triethylamine (8.86 mL, 30.573 mmol) at 0 C and stirred. To this reaction mixture was added methanesulfonyl chloride (2.35 mL, 30.573 mmol) in CH2C12 (5 mL) dropwise over 10 min at 0 C and stirred at the room temperature for 2 h. The reaction was monitored by TLC for complete consumption of compound 95. The reaction mixture was quenched with water (50 mL) and extracted with EtOAc (50 mL x 2). The combined organic layer was washed with brine (50 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford 96 (6 g, crude). 1H NMR (400 MHz, DMSO-d6) delta 3.15 (s, 3H), 4.61 (s, 4H), 7.09 (d, J=2.45 Hz, 1H), 8.09 (d, J=2.45 Hz, 1H). LCMS: 236 (M+H).<\/p>\n

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 956951-01-2.<\/p>\n","protected":false},"excerpt":{"rendered":"

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 956951-01-2.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[454,131],"tags":[126],"class_list":["post-3192","post","type-post","status-publish","format-standard","hentry","category-956951-01-2","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nSimple exploration of 3-Nitro-1H-pyrazole-1-ethanol<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 956951-01-2, name is 3-Nitro-1H-pyrazole-1-ethanol, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 3-Nitro-1H-pyrazole-1-ethanol\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3192\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Simple exploration of 3-Nitro-1H-pyrazole-1-ethanol\" \/>\n<meta property=\"og:description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 956951-01-2, name is 3-Nitro-1H-pyrazole-1-ethanol, This compound has unique chemical properties. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Simple exploration of 3-Nitro-1H-pyrazole-1-ethanol","description":"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 956951-01-2, name is 3-Nitro-1H-pyrazole-1-ethanol, This compound has unique chemical properties. 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