{"id":3138,"date":"2021-04-06T00:00:00","date_gmt":"2021-04-05T16:00:00","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=3138"},"modified":"2021-04-06T00:00:00","modified_gmt":"2021-04-05T16:00:00","slug":"sources-of-common-compounds-5-amino-1-4-methylsulfonylphenyl-1h-pyrazole-4-carbonitrile","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=3138","title":{"rendered":"Sources of common compounds: 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile"},"content":{"rendered":"

106368-32-5, name is 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Safety of 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile<\/a><\/p>\n

A MIXTURE OF 5-AMINO-1- (4-METHANESULFONYL-PHENYL)-LH-PYRAZOLE-4-CARBONITRILE (540 mg), formic acid (10 mL) and 1 mL H2O was refluxed overnight at 102’C. After cooling to room temperature, a white precipitate was observed. The mixture was diluted with H20 (10 mL), filtered through a funnel and washed thoroughly with H20, CH30H, and diethyl ether. The white solid was collected and dried under vacuum to give a crude product (300 mg, 50% YIELD). H NMR (DMSO-D6, 4. 00 MHZ) 5 3. 26 (s, 3H), 8. 12 (d, 2H), 8. 29 (s, 1H), 8. 42 (d, 2H), 8. 44 (d, 1H), 12. 61 (s, 1H). LCMS : calculated C12HoN403S 290. 05, observed 291. 2 (MH+).<\/p>\n

The synthetic route of 106368-32-5 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 106368-32-5 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[507,131],"tags":[127],"class_list":["post-3138","post","type-post","status-publish","format-standard","hentry","category-106368-32-5","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nSources of common compounds: 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile<\/title>\n<meta name=\"description\" content=\"106368-32-5, name is 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Safety of 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=3138\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sources of common compounds: 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile\" \/>\n<meta property=\"og:description\" content=\"106368-32-5, name is 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 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The chemical synthesis route is as follows. Safety of 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=3138","og_locale":"en_US","og_type":"article","og_title":"Sources of common compounds: 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile","og_description":"106368-32-5, name is 5-Amino-1-(4-(methylsulfonyl)phenyl)-1H-pyrazole-4-carbonitrile, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 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