{"id":2625,"date":"2021-03-31T02:35:19","date_gmt":"2021-03-30T18:35:19","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2625"},"modified":"2021-03-31T02:35:19","modified_gmt":"2021-03-30T18:35:19","slug":"a-new-application-about-4-phenyl-3h-124-triazole-354h-dione","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2625","title":{"rendered":"A new application about 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione"},"content":{"rendered":"

Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 4233-33-4, Name is 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione, molecular formula is C8H5N3O2, belongs to pyrazoles-derivatives compound, is a common compound. In a patnet, author is Bhirud, Jayashri D., once mentioned the new application about 4233-33-4, SDS of cas: 4233-33-4<\/a>.<\/p>\n

Sulfamic acid catalyzed synthesis of new 3,5-[(sub)phenyl]-1H-pyrazole bearing N-1-isonicotinoyl: And their pharmacological activity evaluation<\/p>\n

A sustainable synthesis of new 3,5-[(sub)phenyl]-1H-pyrazole bearing N-1-isonicotinoyl derivatives from substituted chalcones and isoniazid by using sulfamic acid and their pharmacological activity evaluation is reported. An anti-oxidant study is performed by using DPPH assay. In vitro anti-mycobacterial activity of compounds bearing R\/R’ = 4-CH3\/4-F and 3-OCH3\/4-Cl showed complete inhibition (99%) at the MIC of 31 and 34 mu M respectively. Antibacterial screening of compounds bearing R\/R’ = 4-CH3\/4-F; 4-OCH3\/4-Br; and 4-OCH3\/4-Cl has shown noticeable inhibition (27 mm) against Staphylococcus aureus. The anti-cancer bioassay demonstrated that the five compounds were active on human breast cancer cell line MCF-7; however on HeLa cervical cancer cells only two compounds are active in comparison to standard drug Doxorubicin. Higher inhibitory effects observed in this study appear to be dependent on the chloro, bromo, fluoro and methoxy functionality present on the aromatic nucleus. The structures of all the compounds are established using NMR (H-1 and C-13), FT-IR, Mass and elemental analysis.<\/p>\n

We\u00a1\u00afll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 4233-33-4. The above is the message from the blog manager. SDS of cas: 4233-33-4<\/a>.<\/p>\n

Reference:
Pyrazole – Wikipedia<\/a>,
,Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

We\u00a1\u00afll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 4233-33-4. The above is the message from the blog manager. SDS of cas: 4233-33-4<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[506,131],"tags":[126],"class_list":["post-2625","post","type-post","status-publish","format-standard","hentry","category-4233-33-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nA new application about<\/title>\n<meta name=\"description\" content=\"Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 4233-33-4, Name is 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione, molecular formula is C8H5N3O2, belongs to pyrazoles-derivatives compound, is a common compound. In a patnet, author is Bhirud, Jayashri D., once mentioned the new application about 4233-33-4, SDS of cas: 4233-33-4.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=2625\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A new application about\" \/>\n<meta property=\"og:description\" content=\"Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 4233-33-4, Name is 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione, molecular formula is C8H5N3O2, belongs to pyrazoles-derivatives compound, is a common compound. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"A new application about","description":"Chemistry is traditionally divided into organic and inorganic chemistry. 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