{"id":2531,"date":"2021-03-25T02:51:34","date_gmt":"2021-03-24T18:51:34","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2531"},"modified":"2021-03-25T02:51:34","modified_gmt":"2021-03-24T18:51:34","slug":"interesting-scientific-research-on-5932-27-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2531","title":{"rendered":"Interesting scientific research on 5932-27-4"},"content":{"rendered":"<p>The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 5932-27-4, Name is Ethyl 1H-pyrazole-3-carboxylate, SMILES is O=C(C1=NNC=C1)OCC, in an article , author is Kadambar, Anish Kumar, once mentioned of 5932-27-4, <a href=\"https:\/\/www.ambeed.com\/products\/5932-27-4.html\">Recommanded Product: Ethyl 1H-pyrazole-3-carboxylate<\/a>.<\/p>\n<p>One-pot three-component azide-alkyne cycloaddition: Synthesis of new pyrazole, 1,2,3-triazole, and oxadiazole tethered and their anti-inflammatory, quantitative structure-activity relationship, and docking studies<\/p>\n<p>A simple and efficient one-pot three-component azide-alkyne cycloaddition of 5-chloro-1-phenyl-pyrazole-4-carbaldehyde with 2-(prop-2-yn-1-ylthio)-5-(substituted phenoxy)methyl-1,3,4-oxadiazole and sodium azide is reported. The newly synthesized compounds were characterized by spectral and analytical data. They were screened for in vitro anti-inflammatory activity by bovine serum albumin denaturation assay. All the tested compounds showed moderate anti-inflammatory activity, whereas three compounds (4d, 4i, and 4k) showed excellent activity comparable with that of the standard drug diclofenac sodium. The quantitative structure-activity relationship (QSAR) study was carried out for anti-inflammatory activities of the synthesized compounds and developed a QSAR model. Inspired by their in vitro anti-inflammatory activities, they were docked to the active site of COX-2 to know the anti-inflammatory potency in silico.<\/p>\n<p>Interested yet? Read on for other articles about 5932-27-4, you can contact me at any time and look forward to more communication. <a href=\"https:\/\/www.ambeed.com\/products\/5932-27-4.html\">Recommanded Product: Ethyl 1H-pyrazole-3-carboxylate<\/a>.<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/>,<a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Interested yet? Read on for other articles about 5932-27-4, you can contact me at any time and look forward to more communication. <a href=\"https:\/\/www.ambeed.com\/products\/5932-27-4.html\">Recommanded Product: Ethyl 1H-pyrazole-3-carboxylate<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[170,131],"tags":[126],"class_list":["post-2531","post","type-post","status-publish","format-standard","hentry","category-5932-27-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Interesting scientific research on<\/title>\n<meta name=\"description\" content=\"The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 5932-27-4, Name is Ethyl 1H-pyrazole-3-carboxylate, SMILES is O=C(C1=NNC=C1)OCC, in an article , author is Kadambar, Anish Kumar, once mentioned of 5932-27-4, Recommanded Product: Ethyl 1H-pyrazole-3-carboxylate.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=2531\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Interesting scientific research on\" \/>\n<meta property=\"og:description\" content=\"The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 5932-27-4, Name is Ethyl 1H-pyrazole-3-carboxylate, SMILES is O=C(C1=NNC=C1)OCC, in an article , author is Kadambar, Anish Kumar, once mentioned of 5932-27-4, Recommanded Product: Ethyl 1H-pyrazole-3-carboxylate.\" \/>\n<meta property=\"og:url\" content=\"http:\/\/www.pyrazoles-derivatives.com\/?p=2531\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-24T18:51:34+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=2531\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=2531\",\"name\":\"Interesting scientific research on\",\"isPartOf\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-03-24T18:51:34+00:00\",\"author\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 5932-27-4, Name is Ethyl 1H-pyrazole-3-carboxylate, SMILES is O=C(C1=NNC=C1)OCC, in an article , author is Kadambar, Anish Kumar, once mentioned of 5932-27-4, Recommanded Product: Ethyl 1H-pyrazole-3-carboxylate.\",\"breadcrumb\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=2531#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\/\/www.pyrazoles-derivatives.com\/?p=2531\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=2531#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"http:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Interesting scientific research on 5932-27-4\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Interesting scientific research on","description":"The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 5932-27-4, Name is Ethyl 1H-pyrazole-3-carboxylate, SMILES is O=C(C1=NNC=C1)OCC, in an article , author is Kadambar, Anish Kumar, once mentioned of 5932-27-4, Recommanded Product: Ethyl 1H-pyrazole-3-carboxylate.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"http:\/\/www.pyrazoles-derivatives.com\/?p=2531","og_locale":"en_US","og_type":"article","og_title":"Interesting scientific research on","og_description":"The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 5932-27-4, Name is Ethyl 1H-pyrazole-3-carboxylate, SMILES is O=C(C1=NNC=C1)OCC, in an article , author is Kadambar, Anish Kumar, once mentioned of 5932-27-4, Recommanded Product: Ethyl 1H-pyrazole-3-carboxylate.","og_url":"http:\/\/www.pyrazoles-derivatives.com\/?p=2531","og_site_name":"pyrazoles-derivatives","article_published_time":"2021-03-24T18:51:34+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"http:\/\/www.pyrazoles-derivatives.com\/?p=2531","url":"http:\/\/www.pyrazoles-derivatives.com\/?p=2531","name":"Interesting scientific research on","isPartOf":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2021-03-24T18:51:34+00:00","author":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 5932-27-4, Name is Ethyl 1H-pyrazole-3-carboxylate, SMILES is O=C(C1=NNC=C1)OCC, in an article , author is Kadambar, Anish Kumar, once mentioned of 5932-27-4, Recommanded Product: Ethyl 1H-pyrazole-3-carboxylate.","breadcrumb":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/?p=2531#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["http:\/\/www.pyrazoles-derivatives.com\/?p=2531"]}]},{"@type":"BreadcrumbList","@id":"http:\/\/www.pyrazoles-derivatives.com\/?p=2531#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"http:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Interesting scientific research on 5932-27-4"}]},{"@type":"WebSite","@id":"http:\/\/www.pyrazoles-derivatives.com\/#website","url":"http:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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