{"id":2356,"date":"2021-03-18T02:55:32","date_gmt":"2021-03-17T18:55:32","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2356"},"modified":"2021-03-18T02:55:32","modified_gmt":"2021-03-17T18:55:32","slug":"a-new-synthetic-route-of-151521-49-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2356","title":{"rendered":"A new synthetic route of 151521-49-2"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 151521-49-2, name is 4-Isopropyl-1H-pyrazol-5-amine, This compound has unique chemical properties. The synthetic route is as follows., name: 4-Isopropyl-1H-pyrazol-5-amine<\/a><\/p>\n

A mixture of methyl 3-(5-bromo-3-pyridyl)-3-oxo-propanoate (300 mg, 813.74 mupiiotaomicron, 1 eq) and 4-isopropyl-lH-pyrazol-5-amine (122.23 mg, 976.49 mupiiotaomicron, 1.2 eq) in AcOH (10 mL) was stirred at 120 C for 0.5 h. The mixture was concentrated under reduced pressure to give 5-(5-bromo-3- pyridyl)-3-isopropyl-pyrazolo[l,5-a]pyrimidin-7-ol (450 mg, crude) as brown oil which was used in next step without further purification. NMR (400 MHz, CDCl3) S ppm 8.99-8.88 (m, 1H), 8.74-8.73 (m, 1H), 8.39-8.37 (m, 2H), 7.79 (s, 1H), 3.21-3.20 (m, 1H), 1.39-1.33 (m, 6H); ES- LCMS m\/z 333.0, 335.0 [M+H].<\/p>\n

According to the analysis of related databases, 151521-49-2, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 151521-49-2, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[422,131],"tags":[126],"class_list":["post-2356","post","type-post","status-publish","format-standard","hentry","category-151521-49-2","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nA new synthetic route of 151521-49-2<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 151521-49-2, name is 4-Isopropyl-1H-pyrazol-5-amine, This compound has unique chemical properties. The synthetic route is as follows., name: 4-Isopropyl-1H-pyrazol-5-amine\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=2356\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A new synthetic route of 151521-49-2\" \/>\n<meta property=\"og:description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 151521-49-2, name is 4-Isopropyl-1H-pyrazol-5-amine, This compound has unique chemical properties. 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