{"id":2275,"date":"2021-03-16T02:45:46","date_gmt":"2021-03-15T18:45:46","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2275"},"modified":"2021-03-16T02:45:46","modified_gmt":"2021-03-15T18:45:46","slug":"the-origin-of-a-common-compound-about-96799-02-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2275","title":{"rendered":"The origin of a common compound about 96799-02-9"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 96799-02-9, name is 5-(Furan-2-yl)-1H-pyrazol-3-amine, This compound has unique chemical properties. The synthetic route is as follows., name: 5-(Furan-2-yl)-1H-pyrazol-3-amine<\/a><\/p>\n

DIPEA (0.13 mL, 0.65 mmol) and 5-(furan-2-yl)-lH-pyrazol-3-amine (87.4 mg, 0.586 mmol) were added to a suspension of compound 4 (0.2g, 0.588 mmol) in THF (12 mL). The mixture was heated at 150 C for 10 minutes using microwave initiator. A solution of N-Methylpiperazine (70.4 mg, 0.703 mmol) and DIPEA ((0.13 mL, 0.65 mmol) in THF (5 mL) was added to the above vial at room temperature. The mixture was heated at 60 0C for 0.2 hours. After cooling to room temperature, saturated NaHCO3 in water was added to the flask and the mixture was extracted with dichloromethane (3 x25 ml) and washed by brine, dried over sodium sulfate and concentrated. The resulting crude product was purified by Teledyne-Isco flash system by using DCM\/MeOH, 0 to 15% of Methanol in dichloromethane to provide compound 30 as light yellow solids (155 mg, 32%). 1 H NMR (400 MHz, DMSO- d6) delta 12.66 (bs, I H), 10.37 (s, IH), 9.79 (s, IH), 7.797.06 (m, 7H1), 6.07 (bs, IH), 3.70 (m, 4H), 2.33 (m, 4H), 2.20 (s, 3H), 1.42 (m, I H), 0.85 (m, 4H) ; ESI-MS: calculated for (C25H27N9O2S) 517, found 518 (MH+). HPLC: retention time: 10.92 min. purity: 96%.<\/p>\n

According to the analysis of related databases, 96799-02-9, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 96799-02-9, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[334,131],"tags":[126],"class_list":["post-2275","post","type-post","status-publish","format-standard","hentry","category-96799-02-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe origin of a common compound about 96799-02-9<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 96799-02-9, name is 5-(Furan-2-yl)-1H-pyrazol-3-amine, This compound has unique chemical properties. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The origin of a common compound about 96799-02-9","description":"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 96799-02-9, name is 5-(Furan-2-yl)-1H-pyrazol-3-amine, This compound has unique chemical properties. 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