{"id":2143,"date":"2021-03-11T02:17:40","date_gmt":"2021-03-10T18:17:40","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2143"},"modified":"2021-03-11T02:17:40","modified_gmt":"2021-03-10T18:17:40","slug":"introduction-of-a-new-synthetic-route-about-368870-03-5","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2143","title":{"rendered":"Introduction of a new synthetic route about 368870-03-5"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 368870-03-5, name is (4-(1H-Pyrazol-1-yl)phenyl)methanamine, A new synthetic method of this compound is introduced below., SDS of cas: 368870-03-5<\/a><\/p>\n

The 9-cyclopentyl-2,6-dichloro-9H-purine (4.70 mmol) was dissolved in a mixture of n-propanol (15.0 ml) and N,N-diisopropyl-N-ethylamine (9.40 mmol) and to the solution 1 -[4-(1H-pyrazol-1 -yl)]phenylmethanamine (1.44 mmol) was added. The reaction mixture was heated in a sealedtube under an argon atmosphere at 100C. for 1.5 hour. Afier cooling to room temperature the resulting solid precipitate was suspended in ethanol (20 ml) and the precipitate was filtered off and washed with ice-cooled ethanol (20 ml). The crude product was dried at 80 C. for 2 hours and finally crystallized from ethanol. Yield: 72%, m.p.: 165-167 C. Elemental analysis: Calcd. for C2QH,9C1N60 (394.86): C, 60.84; H, 4.85; N, 21.28. Found: C, 60.56; H, 4.92; N, 21.48. HPLC-MS (ESI+): 394.3 (97.6%). ?H NMR (DMSO-d5):1. 61-1.71 (m, 2H), 1.80-1.98 (m, 4H), 2.09-2.18 (m, 2H), 4.66 (d, J=5.25, 2H, CH2), 4.77 (qui, J=7.05, 1H, CH), 6.51 (t, J=2.16, 1H,ArH), 7.45 (d, J=8.37, 2H,ArH), 7.71 (d, J=2.16, 1H, ArH), 7.77 (d, J=8.37, 2H, ArH), 8.27 (s, 1H, CH), 8.43 (d, J=2.16, 1H, ArH), 8.86 (t, J=5.25, 1H, NH)<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[322,131],"tags":[126],"class_list":["post-2143","post","type-post","status-publish","format-standard","hentry","category-368870-03-5","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nIntroduction of a new synthetic route about 368870-03-5<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 368870-03-5, name is (4-(1H-Pyrazol-1-yl)phenyl)methanamine, A new synthetic method of this compound is introduced below., SDS of cas: 368870-03-5\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=2143\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Introduction of a new synthetic route about 368870-03-5\" \/>\n<meta property=\"og:description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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