{"id":2123,"date":"2021-03-10T02:49:46","date_gmt":"2021-03-09T18:49:46","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2123"},"modified":"2021-03-10T02:49:46","modified_gmt":"2021-03-09T18:49:46","slug":"analyzing-the-synthesis-route-of-29969-57-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2123","title":{"rendered":"Analyzing the synthesis route of 29969-57-1"},"content":{"rendered":"<p>29969-57-1, name is 2-Chloro-6-nitroquinoline, belongs to quinolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. <a href=\"https:\/\/www.ambeed.com\/products\/29969-57-1.html\">name: 2-Chloro-6-nitroquinoline<\/a><\/p>\n<p>General procedure: To a solution of substituted quinolines (5a-b) (1.0-1.5equiv.), compound 8 (1.0equiv.) in degassed 1,4-dioxane were added Pd2(dba)3 (0.1-0.2 equiv.), t-butylXphos (0.1-0.2equiv.), and Cy2NMe (2.0 equiv.). The solution was stirred under N2 at 120C for 18-40h. The mixture was filtered through Celite and washed with EtOAc. The solution was washed with water and brine, and dried with Na2SO4. The crude material was purified by column chromatography (silica gel, Hexane\/EtOAc).<\/p>\n<p>The synthetic route of 29969-57-1 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The synthetic route of 29969-57-1 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[439,427],"tags":[127],"class_list":["post-2123","post","type-post","status-publish","format-standard","hentry","category-29969-57-1","category-quinolines-derivatives","tag-m-w200-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Analyzing the synthesis route of 29969-57-1<\/title>\n<meta name=\"description\" content=\"29969-57-1, name is 2-Chloro-6-nitroquinoline, belongs to quinolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. 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