{"id":2112,"date":"2021-03-10T02:49:46","date_gmt":"2021-03-09T18:49:46","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2112"},"modified":"2021-03-10T02:49:46","modified_gmt":"2021-03-09T18:49:46","slug":"introduction-of-a-new-synthetic-route-about-5234-86-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2112","title":{"rendered":"Introduction of a new synthetic route about 5234-86-6"},"content":{"rendered":"

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 5234-86-6 as follows. Quality Control of 2,3,4,6,7,11b-Hexahydro-1H-pyrazino[2,1-a]isoquinoline<\/a><\/p>\n

General procedure: To a stirred solution of compound 16 (500 mg, 2.7 mmol) in DCM (50 mL), cyclohexanecarbonyl chloride (532 L, 4.0 mmol) was added at 0 C. The mixture was stirred at room temperature overnight. The reaction was quenched with NaHCO3 (aq.), extracted with DCM (50 mL \u00a1\u00c1 3). The organic phases were then processed in the usual way and chromatographed (1:1 petroleum ether\/ EtOAc) to afforded compound 19 (350 mg, 43%) as white solid.<\/p>\n

According to the analysis of related databases, 5234-86-6, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 5234-86-6, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[429,427],"tags":[126],"class_list":["post-2112","post","type-post","status-publish","format-standard","hentry","category-5234-86-6","category-quinolines-derivatives","tag-m-w100-200"],"yoast_head":"\nIntroduction of a new synthetic route about 5234-86-6<\/title>\n<meta name=\"description\" content=\"In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 5234-86-6 as follows. 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