{"id":2089,"date":"2021-03-09T03:21:55","date_gmt":"2021-03-08T19:21:55","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2089"},"modified":"2021-03-09T03:21:55","modified_gmt":"2021-03-08T19:21:55","slug":"extended-knowledge-of-5334-40-7-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2089","title":{"rendered":"Extended knowledge of 5334-40-7"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 5334-40-7, name is 4-Nitro-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5334-40-7, Formula: C4H3N3O4<\/a><\/p>\n

To a solution of 4-nitro-1H-pyrazole-3-carboxylic acid (1.00 g, 6.37 mmol) in DMF (20 mL) were added K2C03 (1.93 g, 14.01 mmol) and iodomethane (1.99 g, 14.01 mmol), and the mixture was stirred at rt overnight under nitrogen. Water (50 mL) was added and the mixture was extracted with EtOAc (3 x 60 mL). The combined organic layers were washed with brine (25 mL), dried over anhydrous Na2SO4 and concentrated. The residue was purified by silica gel chromatography eluting with petroleum ether EtOAc (8: ito 1:2) to afford methyl 1- methyl-4-nitro- 1H-pyrazole-3-carboxylate.<\/p>\n

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"excerpt":{"rendered":"

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[153,131],"tags":[126],"class_list":["post-2089","post","type-post","status-publish","format-standard","hentry","category-5334-40-7","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nExtended knowledge of 5334-40-7<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 5334-40-7, name is 4-Nitro-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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