{"id":2071,"date":"2021-03-09T03:21:16","date_gmt":"2021-03-08T19:21:16","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2071"},"modified":"2021-03-09T03:21:16","modified_gmt":"2021-03-08T19:21:16","slug":"extracurricular-laboratory-synthetic-route-of-56426-35-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2071","title":{"rendered":"Extracurricular laboratory: Synthetic route of 56426-35-8"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 56426-35-8, name is Methyl 5-phenyl-1H-pyrazole-3-carboxylate, A new synthetic method of this compound is introduced below., name: Methyl 5-phenyl-1H-pyrazole-3-carboxylate<\/a><\/p>\n

Intermediate 96 (320mg, 1.58mmol) was dissolved in THF\/water (15mL, 1 :1), lithium hydroxide monohydrate (146mg, 3.48mmol) was added and the reaction mixture was stirred for 2h. The THF was removed in vacuo and the aqueous solution was acidified to pH 1 with 1M aq HCl. The precipitate was collected by filtration to give the title compound (232mg, 78%) as a yellow solid. LCMS: ES+ 189.0 [MH]+.<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[274,131],"tags":[127],"class_list":["post-2071","post","type-post","status-publish","format-standard","hentry","category-56426-35-8","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nExtracurricular laboratory: Synthetic route of 56426-35-8<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 56426-35-8, name is Methyl 5-phenyl-1H-pyrazole-3-carboxylate, A new synthetic method of this compound is introduced below., name: Methyl 5-phenyl-1H-pyrazole-3-carboxylate\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=2071\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Extracurricular laboratory: Synthetic route of 56426-35-8\" \/>\n<meta property=\"og:description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 56426-35-8, name is Methyl 5-phenyl-1H-pyrazole-3-carboxylate, A new synthetic method of this compound is introduced below., name: Methyl 5-phenyl-1H-pyrazole-3-carboxylate\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=2071\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-08T19:21:16+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=2071\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=2071\",\"name\":\"Extracurricular laboratory: Synthetic route of 56426-35-8\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-03-08T19:21:16+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/cn.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/cn.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Extracurricular laboratory: Synthetic route of 56426-35-8","description":"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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