{"id":2061,"date":"2021-03-08T05:23:37","date_gmt":"2021-03-07T21:23:37","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2061"},"modified":"2021-03-08T05:23:37","modified_gmt":"2021-03-07T21:23:37","slug":"some-scientific-research-about-129768-30-5","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2061","title":{"rendered":"Some scientific research about 129768-30-5"},"content":{"rendered":"<p><a href=\"https:\/\/www.ambeed.com\/products\/129768-30-5.html\">Related Products of 129768-30-5<\/a>, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 129768-30-5, name is Ethyl 3-(Trifluoromethyl)pyrazole-5-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.<\/p>\n<p>To a solution of ethyl 3-(trifluoromethyl)-li\/-pyrazole-5-carboxylate (1.00 g, 4.80 mmol) in l,2-dichloroethane (40 mL) were added cyclopropylboronic acid (0.825 g, 9.61 mmol) and sodium carbonate (1.02 g, 9.61 mmol). The reaction mixture was warmed to 70 C and 2,2&#8242;- bipyridine (0.750 g, 4.80 mmol) and copper(II) acetate (0.873 g, 4.80 mmol) were added and the reaction mixture was allowed to stir for 18 h at 70 C. The reaction mixture was cooled to ambient temperature and diluted with a saturated aqueous solution of sodium bicarbonate and extracted with ethyl acetate (2 x). The combined organic extracts were washed with a saturated aqueous solution of sodium chloride and concentrated under reduced pressure. The residue was purified by silica gel chromatography, eluting with a gradient of hexanes: ethyl acetate &#8211; 95:5 to 50:50 to afford the title compound. MS: m\/z = 249.1 [M+H]<\/p>\n<p>The synthetic route of Ethyl 3-(Trifluoromethyl)pyrazole-5-carboxylate has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The synthetic route of Ethyl 3-(Trifluoromethyl)pyrazole-5-carboxylate has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[418,131],"tags":[127],"class_list":["post-2061","post","type-post","status-publish","format-standard","hentry","category-129768-30-5","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Some scientific research about 129768-30-5<\/title>\n<meta name=\"description\" content=\"Related Products of 129768-30-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 129768-30-5, name is Ethyl 3-(Trifluoromethyl)pyrazole-5-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=2061\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Some scientific research about 129768-30-5\" \/>\n<meta property=\"og:description\" content=\"Related Products of 129768-30-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 129768-30-5, name is Ethyl 3-(Trifluoromethyl)pyrazole-5-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=2061\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-07T21:23:37+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=2061\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=2061\",\"name\":\"Some scientific research about 129768-30-5\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-03-07T21:23:37+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Related Products of 129768-30-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 129768-30-5, name is Ethyl 3-(Trifluoromethyl)pyrazole-5-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=2061#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=2061\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=2061#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Some scientific research about 129768-30-5\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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