{"id":2032,"date":"2021-03-08T05:22:26","date_gmt":"2021-03-07T21:22:26","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2032"},"modified":"2021-03-08T05:22:26","modified_gmt":"2021-03-07T21:22:26","slug":"new-learning-discoveries-about-27116-80-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2032","title":{"rendered":"New learning discoveries about 27116-80-9"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 27116-80-9, name is 3-Methyl-4-nitro-5-(trifluoromethyl)-1H-pyrazole, A new synthetic method of this compound is introduced below., Computed Properties of C5H4F3N3O2<\/a><\/p>\n

Step 1. Synthesis of 4-nitro-5-(trifluoromethyl’)-1\/-\/-pyrazole-3-carboxylic acid (C37V Potassium permanganate (56.7 g, 359 mmol) was added to a solution of 3-methyl-4-nitro-5- (trifluoromethyl)-I H-pyrazole (prepared from 3-methyl-5-(trifluoromethyl)-1 \/-\/-pyrazole as described by B. A. Acker et ai, PCT Int. Appl. 2006, WO 2006046135; 20.0 g, 102.5 mmol) in water (400 imL), and the reaction mixture was heated at 100 C for 12 hours. The mixture was passed through a pad of Celite, and the filtrate was acidified with concentrated HCI, then extracted with EtOAc. The combined organic layers were dried over sodium sulfate, filtered and concentrated in vacuo to afford C37 as a white solid. Yield: 20.0 g, 88.9 mmol, 87%. LCMS m\/z 224.0 (M-1 ). 3C NMR (75 MHz, DMSO-d6) delta 1 19.5 (q, JCF=269 Hz), 130.9, 133.7, 134.4 (q, JCF=39 Hz), 157.4.<\/p>\n

The synthetic route of 27116-80-9 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 27116-80-9 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[410,131],"tags":[126],"class_list":["post-2032","post","type-post","status-publish","format-standard","hentry","category-27116-80-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nNew learning discoveries about 27116-80-9<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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