{"id":2016,"date":"2021-03-05T04:51:17","date_gmt":"2021-03-04T20:51:17","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2016"},"modified":"2021-03-05T04:51:17","modified_gmt":"2021-03-04T20:51:17","slug":"new-downstream-synthetic-route-of-288-13-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2016","title":{"rendered":"New downstream synthetic route of 288-13-1"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 288-13-1, name is 1H-Pyrazole, A new synthetic method of this compound is introduced below., category: pyrazoles-derivatives<\/a><\/p>\n

3.40 g (0.05 mol) of pyrazoleAnd 2.8g (0.05mol) powdered KOH were added to a 100mL three-necked flask,Add 10mLDMSO as a solvent, the mixture was stirred at 80 for 30min,Then 6.25 g (0.05 mol) of 2-bromoethanol was added (added to the flask in 30 mL intervals, three times)Continue stirring for 20 ~ 30h, cooled to room temperature,After filtration, 20 mL of chloroform was added and the solution was washed with water (5 \u00a1\u00c1 20 mL)Rotary drying to give a colorless transparent liquid 1-ethylpyrazole (yield: 60 ~ 70%).<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[149,131],"tags":[145],"class_list":["post-2016","post","type-post","status-publish","format-standard","hentry","category-288-13-1","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"\nNew downstream synthetic route of 288-13-1<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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