{"id":2009,"date":"2021-03-05T04:51:17","date_gmt":"2021-03-04T20:51:17","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=2009"},"modified":"2021-03-05T04:51:17","modified_gmt":"2021-03-04T20:51:17","slug":"share-a-compound-4149-06-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=2009","title":{"rendered":"Share a compound : 4149-06-8"},"content":{"rendered":"

Some common heterocyclic compound, 4149-06-8, name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, molecular formula is C9H9N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Application In Synthesis of 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one<\/a><\/p>\n

General procedure: The mixture of alpha,beta-unsaturated ketone 1, or 4 (1.0 mmol), 3-amino-1-phenyl-1H-pyrazol-5(4H)-one 2 (1.0 mmol), p-TSAxH2O (0.3mmol), MeCN (4mL), H2O (4mL) was put in a reaction flask under 80 C about 1-3 h (monitored by TLC). After completion, the reaction mixture was cooled to room temperature and the products would be precipitated out at same time. Then, it was filtered, washed thoroughly with MeCN. The products were recrystallized from DMF.<\/p>\n

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 4149-06-8, its application will become more common.<\/p>\n","protected":false},"excerpt":{"rendered":"

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 4149-06-8, its application will become more common.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[283,131],"tags":[126],"class_list":["post-2009","post","type-post","status-publish","format-standard","hentry","category-4149-06-8","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nShare a compound : 4149-06-8<\/title>\n<meta name=\"description\" content=\"Some common heterocyclic compound, 4149-06-8, name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, molecular formula is C9H9N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Application In Synthesis of 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=2009\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Share a compound : 4149-06-8\" \/>\n<meta property=\"og:description\" content=\"Some common heterocyclic compound, 4149-06-8, name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, molecular formula is C9H9N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 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Application In Synthesis of 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=2009","og_locale":"en_US","og_type":"article","og_title":"Share a compound : 4149-06-8","og_description":"Some common heterocyclic compound, 4149-06-8, name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, molecular formula is C9H9N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 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