{"id":1982,"date":"2021-03-03T05:06:35","date_gmt":"2021-03-02T21:06:35","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1982"},"modified":"2021-03-03T05:06:35","modified_gmt":"2021-03-02T21:06:35","slug":"new-learning-discoveries-about-1222174-92-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1982","title":{"rendered":"New learning discoveries about 1222174-92-6"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 1222174-92-6, name is Methyl 5-bromo-1-methyl-1H-pyrazole-3-carboxylate, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1222174-92-6, Recommanded Product: Methyl 5-bromo-1-methyl-1H-pyrazole-3-carboxylate<\/a><\/p>\n

A solution of intermediate 2a (515 mg), 2,5-dimethoxyphenylboronic acid (642 mg) and Pd(dppf)Cl2.CH2Cl2 (105 mg) in a mixture of THF (15 mL) and sodium carbonate solution (2 M, 3 mL) was heated in a microwave (Biotage) to 100 C. for 1.5 h. The mixture was chilled, the layers separated and the aqueous layer was extracted with EtOAc. The combined organic layers were dried and the volatiles were removed under reduced pressure. The residue was purified by chromatography (Interchim cartridge 50SiHP\/25 g, Cy\/EtOAc) to yield the desired compound (77% yield). [0349] LC-MS (Method 2): m\/z [M+H]+=277.1 (MW calc.=276.29); Rt=0.62 min.<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 5-bromo-1-methyl-1H-pyrazole-3-carboxylate, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 5-bromo-1-methyl-1H-pyrazole-3-carboxylate, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[275,131],"tags":[127],"class_list":["post-1982","post","type-post","status-publish","format-standard","hentry","category-1222174-92-6","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nNew learning discoveries about 1222174-92-6<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 1222174-92-6, name is Methyl 5-bromo-1-methyl-1H-pyrazole-3-carboxylate, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"New learning discoveries about 1222174-92-6","description":"Adding a certain compound to certain chemical reactions, such as: 1222174-92-6, name is Methyl 5-bromo-1-methyl-1H-pyrazole-3-carboxylate, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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