{"id":1971,"date":"2021-03-03T05:06:35","date_gmt":"2021-03-02T21:06:35","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1971"},"modified":"2021-03-03T05:06:35","modified_gmt":"2021-03-02T21:06:35","slug":"research-on-new-synthetic-routes-about-51516-70-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1971","title":{"rendered":"Research on new synthetic routes about 51516-70-2"},"content":{"rendered":"

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 51516-70-2, name is 5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbonitrile belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 51516-70-2<\/a><\/p>\n

General procedure: (General method). Amixture of the appropriate aminonitrile 1 (3.0 mmol) and1,3-dicarbonyl compound (3.0 mmol) in anhydrous toluene(12 ml) was refluxed for 1 h in a flask equipped with aDean-Stark trap. Tin(IV) chloride (3.0 g, 11.5 mmol) wasadded to the reaction mixture, and refluxing was continuedfor additional 5-6 h. A resinous precipitate was formed,andthe colorless toluene layer was decanted. The residualsolvent was removed on a rotary evaporator, the obtainedglassy solids were dissolved in boiling dioxane, cooled, thenpoured into a solution of Na23 (4.0 g) in water (70 ml).The precipitate that formed was filtered off, washed withwater, dried, and recrystallized from a 5:1 mixture of2-PrOH-DMF.<\/p>\n

The synthetic route of 51516-70-2 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 51516-70-2 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[332,131],"tags":[127],"class_list":["post-1971","post","type-post","status-publish","format-standard","hentry","category-51516-70-2","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nResearch on new synthetic routes about 51516-70-2<\/title>\n<meta name=\"description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 51516-70-2, name is 5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbonitrile belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. 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