{"id":1947,"date":"2021-03-02T05:18:48","date_gmt":"2021-03-01T21:18:48","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1947"},"modified":"2021-03-02T05:18:48","modified_gmt":"2021-03-01T21:18:48","slug":"brief-introduction-of-118430-74-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1947","title":{"rendered":"Brief introduction of 118430-74-3"},"content":{"rendered":"

Application of 118430-74-3<\/a>, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 118430-74-3, name is 3-Cyclopropyl-1-methyl-1H-pyrazol-5-amine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.<\/p>\n

Phenyl {3-[(2-aminopyrimidin-5-yl) ethynyl] phenyl} carbamate (Example 23) (100 mg), triethylamine (0.06 mL) and 3-cyclopropyl-1-methyl-lH-pyrazol-5-amine (60.0 mg) in THF (3 mL) were irradiated under microwave conditions (CEM explorer, 80C, 50W) for 60 min. The reaction mixture was concentrated in vacuo, purification by flash chromatography on silica using 1-10% MeOH in DCM as eluent to give the title compound as a cream solid (46 mg, 37%); ‘H NMR (DMSO-d6) 0.52-0. 59 (m, 2H), 0.76-0. 85 (m, 1H), 1.52 (s, 9H), 1.71-1. 82 (m, 1H), 5. 80 (s, 1H), 7.05-7. 08 (m, 1H), 7.09 (bs, 2H), 7.21-7. 35 (m, 2H), 7.70 (s, 1H), 7.90 (s, 1H), 8.40 (s, 2H), 8.94 (bs, 1H) ; MS m\/e MH+ 416.<\/p>\n

The synthetic route of 3-Cyclopropyl-1-methyl-1H-pyrazol-5-amine has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 3-Cyclopropyl-1-methyl-1H-pyrazol-5-amine has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[233,131],"tags":[126],"class_list":["post-1947","post","type-post","status-publish","format-standard","hentry","category-118430-74-3","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nBrief introduction of 118430-74-3<\/title>\n<meta name=\"description\" content=\"Application of 118430-74-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 118430-74-3, name is 3-Cyclopropyl-1-methyl-1H-pyrazol-5-amine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=1947\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brief introduction of 118430-74-3\" \/>\n<meta property=\"og:description\" content=\"Application of 118430-74-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 118430-74-3, name is 3-Cyclopropyl-1-methyl-1H-pyrazol-5-amine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta property=\"og:url\" content=\"http:\/\/www.pyrazoles-derivatives.com\/?p=1947\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-01T21:18:48+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=1947\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=1947\",\"name\":\"Brief introduction of 118430-74-3\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-03-01T21:18:48+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Application of 118430-74-3, In the next few decades, the world population will flourish. 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