{"id":1945,"date":"2021-03-02T05:18:48","date_gmt":"2021-03-01T21:18:48","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1945"},"modified":"2021-03-02T05:18:48","modified_gmt":"2021-03-01T21:18:48","slug":"analyzing-the-synthesis-route-of-3524-32-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1945","title":{"rendered":"Analyzing the synthesis route of 3524-32-1"},"content":{"rendered":"

3524-32-1, name is 5-Amino-1,3-dimethylpyrazole, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. category: pyrazoles-derivatives<\/a><\/p>\n

General procedure: Compound m22 (1 eq.), amines (1 eq.), 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (1.6 eq.) and 1-hydroxybenzotriazole (1.6 eq.) were dissolved in N,N-dimethylformamide. N,N-Diisopropylethylamine (3.6 eq.) was added to the solution. The mixture was stirred at room temperature overnight. The mixture was added water and extracted with ethyl acetate. The organic layer was washed with brine, dried with Na2SO4, concentrated and purified with sil gel chromatography to get the corresponding product.<\/p>\n

The synthetic route of 3524-32-1 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 3524-32-1 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[139,131],"tags":[126],"class_list":["post-1945","post","type-post","status-publish","format-standard","hentry","category-3524-32-1","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nAnalyzing the synthesis route of 3524-32-1<\/title>\n<meta name=\"description\" content=\"3524-32-1, name is 5-Amino-1,3-dimethylpyrazole, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. 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