{"id":1911,"date":"2021-02-26T05:09:18","date_gmt":"2021-02-25T21:09:18","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1911"},"modified":"2021-02-26T05:09:18","modified_gmt":"2021-02-25T21:09:18","slug":"the-important-role-of-35100-92-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1911","title":{"rendered":"The important role of 35100-92-6"},"content":{"rendered":"

Application of 35100-92-6<\/a>, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 35100-92-6, name is 1,5-Dimethyl-1H-pyrazol-3-amine, This compound has unique chemical properties. The synthetic route is as follows.<\/p>\n

Combine c\/s-4-[(4-bromo- I -methyi-1H-benzimidazoi-6-vi)oxyj cyciohexanamine(25.70 g, 79.27 rnrnol), 1.5-dimethyi-1H-pyrazol-3-arnine (9.08 g, 1.0 eq), potassiumcarbonate (28.48 g, 2.6 eq), 2-(dicyclohexvlphosphino)3,6-dimethoxy-2?,4?,6?- tisopropyi- 1,1 ?-biphenyl (8.60 g, 0,20 eq), tris(dibenzylideneacetone)dipailadium(0) (3.63 g, 0.050 eq), and acetic acid (0.14 rnL) in tert-butyl alcohol (250 mL). Heat at reflux overnight. Concentrate the reaction mixture in vacuo. Add DCM and water;separate the layers. Dry the organics over anhydrous magnesium sulfate, filter, and concentrate in vacuo. Triturate from EtOAc and hexanes to give a tan solid. Subject the tan solid to normal phase chromatography, eluting with hexanes, then 5% MeOFI in DCM, then 20% 2M amrnoniated MeOH in DCM, to give the title compound as a tan solid (21,71 g, 77%). MS (ES) m\/z = 355 (M-t-H).<\/p>\n

The chemical industry reduces the impact on the environment during synthesis 1,5-Dimethyl-1H-pyrazol-3-amine. I believe this compound will play a more active role in future production and life.<\/p>\n","protected":false},"excerpt":{"rendered":"

The chemical industry reduces the impact on the environment during synthesis 1,5-Dimethyl-1H-pyrazol-3-amine. I believe this compound will play a more active role in future production and life.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[136,131],"tags":[126],"class_list":["post-1911","post","type-post","status-publish","format-standard","hentry","category-35100-92-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of 35100-92-6<\/title>\n<meta name=\"description\" content=\"Application of 35100-92-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 35100-92-6, name is 1,5-Dimethyl-1H-pyrazol-3-amine, This compound has unique chemical properties. The synthetic route is as follows.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1911\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The important role of 35100-92-6\" \/>\n<meta property=\"og:description\" content=\"Application of 35100-92-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 35100-92-6, name is 1,5-Dimethyl-1H-pyrazol-3-amine, This compound has unique chemical properties. 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