{"id":1869,"date":"2021-02-24T05:15:24","date_gmt":"2021-02-23T21:15:24","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1869"},"modified":"2021-02-24T05:15:24","modified_gmt":"2021-02-23T21:15:24","slug":"extended-knowledge-of-1752-88-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1869","title":{"rendered":"Extended knowledge of 1752-88-1"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 1752-88-1, name is 3-Pyrazolidinone hydrochloride, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1752-88-1, name: 3-Pyrazolidinone hydrochloride<\/a><\/p>\n

EXAMPLE X31 1-[10-(4-Acetonylphenoxy)decyl]pyrazolidin-3-one. A mixture of 10-(4-acetonylphenoxy)decylbromide, ethylene ketal (3.0 g), potassium carbonate (3.8 g), pyrazolidin-3-one hydrochloride (1.47 g) and potassium iodide (0.5 g) in acetonitrile:water (95:5), was heated under reflux for 3 hr. The reaction mixture was allowed to cool, filtered and the solvent evaporated in vacuo. The residue was dissolved in chloroform, washed with water (2*50 ml), dried (magnesium sulphate), fitered and the solvent removed in vacuo. The residue was dissolved in acetone (50 ml) and treated with 2M hydrochloric acid solution (3 ml) and allowed to stand at room temperature for 3 hr. The solvent was removed in vacuo and the residue was dissolved in chloroform and washed with 1.2M sodium bicarbonate solution (1*50 ml), water (2*50 ml), dried (magnesium sulphate), filtered and the solvent removed in vacuo to give 1-[10-(4-acetonylphenoxy)decyl]pyrazolidin-3-one (0.66 g). 1 H NMR (CDCl3) ppm: 1.1-2.1(16H,m); 2.2(3H,s); 2.3-3.0(4H,m); 3.3(2H,m); 3.7(2H,s); 4.0(2H,m); 7.1(4H,dd); 8.0-92(1H, very broad, exchanges with D2 O).<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Pyrazolidinone hydrochloride, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Pyrazolidinone hydrochloride, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[297,131],"tags":[126],"class_list":["post-1869","post","type-post","status-publish","format-standard","hentry","category-1752-88-1","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nExtended knowledge of 1752-88-1<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 1752-88-1, name is 3-Pyrazolidinone hydrochloride, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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