{"id":1866,"date":"2021-02-24T05:15:24","date_gmt":"2021-02-23T21:15:24","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1866"},"modified":"2021-02-24T05:15:24","modified_gmt":"2021-02-23T21:15:24","slug":"the-important-role-of-1260243-04-6-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1866","title":{"rendered":"The important role of 1260243-04-6"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1260243-04-6, name is Ethyl 5-amino-1H-pyrazole-4-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C6H9N3O2<\/a><\/p>\n

Cs2CO3 (64.20 g, 197.20 mmol) was added to a solution of ethyl 5-amino-1H-pyrazole- 4-carboxylate (20.40 g, 131.40 mmol) and ethyl-3-ethoxyacrylate (28.6 mL, 197.20 mmol) in DMF (250 mL). The reaction mixture was stirred at 110 \u00a1\u00e3C for 16 h. The mixture was cooled to room temp and the pH was adjusted to 4 by the addition of AcOH (80 mL). The mixture was concentrated in vacuo and the residue partitioned between CH2Cl2 H2O (1000 mL, 1:1). The organic layer was separated and the aqueous layer was extracted with CH2Cl2 (3 X 500 mL). The combined organics were washed with brine, dried (MgS04) and concentrated. The crude residue was suspended in EtOH (300 mL) and heated to boiling. After cooling to room temperature the solid was collected by filtration, rinsed with EtOH, then Et20 and dried under vacuum to give ethyl 5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-3-carboxylate (25.16 g, 92 percent). MS (ESI) calcd for C9H9N3O3 (m\/z): 207.06; found: 208 [M+H]<\/p>\n

According to the analysis of related databases, 1260243-04-6, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 1260243-04-6, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[213,131],"tags":[126],"class_list":["post-1866","post","type-post","status-publish","format-standard","hentry","category-1260243-04-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of 1260243-04-6<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1260243-04-6, name is Ethyl 5-amino-1H-pyrazole-4-carboxylate, This compound has unique chemical properties. 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