{"id":1791,"date":"2021-02-19T05:11:15","date_gmt":"2021-02-18T21:11:15","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1791"},"modified":"2021-02-19T05:11:15","modified_gmt":"2021-02-18T21:11:15","slug":"simple-exploration-of-10199-57-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1791","title":{"rendered":"Simple exploration of 10199-57-2"},"content":{"rendered":"

10199-57-2, name is 5-Methyl-1-phenyl-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 5-Methyl-1-phenyl-1H-pyrazole-3-carboxylic acid<\/a><\/p>\n

General procedure: EDCI (1.1 equiv.) and HOBt (1.1 equiv) were added to a solution of the intermediate acid compound 1a-j (1 equiv.) in anhydrous DMF. The reaction mixture was stirred for 1h at ambient temperature, and the L-serine ester (1.1 equiv.) and DIEA (3 equiv.) were added. The solution was heated to 70C for 6h and then cooled to room temperature. The reaction mixture was poured into ice water, and the resulting solid was filtered and dried to give the desired compound.<\/p>\n

The synthetic route of 10199-57-2 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 10199-57-2 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[374,131],"tags":[127],"class_list":["post-1791","post","type-post","status-publish","format-standard","hentry","category-10199-57-2","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nSimple exploration of 10199-57-2<\/title>\n<meta name=\"description\" content=\"10199-57-2, name is 5-Methyl-1-phenyl-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 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