{"id":1775,"date":"2021-02-19T05:11:15","date_gmt":"2021-02-18T21:11:15","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1775"},"modified":"2021-02-19T05:11:15","modified_gmt":"2021-02-18T21:11:15","slug":"share-a-compound-5203-77-0","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1775","title":{"rendered":"Share a compound : 5203-77-0"},"content":{"rendered":"

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5203-77-0, name is 1,3-Dimethyl-1H-pyrazol-5-ol belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. name: 1,3-Dimethyl-1H-pyrazol-5-ol<\/a><\/p>\n

At room temperature, 1,3-dimethyl-1H-pyrazole-5-ol (1.12 g, 0.01 mol) and (1.58 g, 0.02 mol) pyridine were sequentially dissolved in 20 ml of dichloromethane. The low temperature bath was cooled to 0 C. To the above mixture was added dropwise a solution of 3,7-dichloroquinoline-8-acyl chloride (2.73 g, 0.0105 mol) in dichloromethane (10 ml),The dropping rate was 5 drops \/ 30 seconds. After the addition was complete, the mixture naturally rose to room temperature and reacted for 4 hours. To the reaction mixture was added 10 ml of a saturated aqueous sodium hydrogen carbonate solution, and the mixture was extracted with dichloromethane (3 * 15 ml). The organic layers were combined,Wash with water (1 * 15ml), saturated brine, and dry over anhydrous magnesium sulfate. desolvate under reduced pressure to obtain 2.52 g of product with a yield of 75%<\/p>\n

The synthetic route of 5203-77-0 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 5203-77-0 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[253,131],"tags":[126],"class_list":["post-1775","post","type-post","status-publish","format-standard","hentry","category-5203-77-0","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nShare a compound : 5203-77-0<\/title>\n<meta name=\"description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5203-77-0, name is 1,3-Dimethyl-1H-pyrazol-5-ol belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. name: 1,3-Dimethyl-1H-pyrazol-5-ol\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1775\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Share a compound : 5203-77-0\" \/>\n<meta property=\"og:description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5203-77-0, name is 1,3-Dimethyl-1H-pyrazol-5-ol belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. name: 1,3-Dimethyl-1H-pyrazol-5-ol\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1775\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-02-18T21:11:15+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1775\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1775\",\"name\":\"Share a compound : 5203-77-0\",\"isPartOf\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-02-18T21:11:15+00:00\",\"author\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"In the next few decades, the world population will flourish. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Share a compound : 5203-77-0","description":"In the next few decades, the world population will flourish. 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