{"id":1755,"date":"2021-02-18T05:48:17","date_gmt":"2021-02-17T21:48:17","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1755"},"modified":"2021-02-18T05:48:17","modified_gmt":"2021-02-17T21:48:17","slug":"brief-introduction-of-4149-06-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1755","title":{"rendered":"Brief introduction of 4149-06-8"},"content":{"rendered":"

Reference of 4149-06-8<\/a>, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 4149-06-8 name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.<\/p>\n

A solution of 3-amino-1-phenyl-2-pyrazolin-5-one 1 (0.35 g, 2 mmol), dimedone 2 (0.28 g, 2 mmol), aldehyde 3 (0.28 mg, 2 mmol) and Cell-LA-TEA+\/Fe3O4 nanocatalyst (0.03 g, 0.09 mol%) in H2O\/EtOH (3:2) was subjected to ultrasonic irradiation (ultrasonic bath, room temperature). The progress of the reaction was controlled by TLC (hexane\/ethyl acetate, 2:3). After reaction completion, the nanocatalyst was separated magnetically from the reaction mixture and used for subsequent cycles after washing with ethanol. By cooling the reaction solution, the solid product was collected, separated and recrystallized from methanol to get the pure product.<\/p>\n

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, and friends who are interested can also refer to it.<\/p>\n","protected":false},"excerpt":{"rendered":"

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, and friends who are interested can also refer to it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[283,131],"tags":[126],"class_list":["post-1755","post","type-post","status-publish","format-standard","hentry","category-4149-06-8","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nBrief introduction of 4149-06-8<\/title>\n<meta name=\"description\" content=\"Reference of 4149-06-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 4149-06-8 name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=1755\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brief introduction of 4149-06-8\" \/>\n<meta property=\"og:description\" content=\"Reference of 4149-06-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 4149-06-8 name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, This compound is widely used in many fields, so it is necessary to find a new synthetic route. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Brief introduction of 4149-06-8","description":"Reference of 4149-06-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 4149-06-8 name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"http:\/\/www.pyrazoles-derivatives.com\/?p=1755","og_locale":"en_US","og_type":"article","og_title":"Brief introduction of 4149-06-8","og_description":"Reference of 4149-06-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 4149-06-8 name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, This compound is widely used in many fields, so it is necessary to find a new synthetic route. 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