{"id":1746,"date":"2021-02-10T05:17:53","date_gmt":"2021-02-09T21:17:53","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1746"},"modified":"2021-02-10T05:17:53","modified_gmt":"2021-02-09T21:17:53","slug":"discovery-of-1191616-45-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1746","title":{"rendered":"Discovery of 1191616-45-1"},"content":{"rendered":"

Synthetic Route of 1191616-45-1<\/a>, The chemical industry reduces the impact on the environment during synthesis 1191616-45-1, name is 4-(4-Bromophenyl)-1-methyl-1H-pyrazole, I believe this compound will play a more active role in future production and life.<\/p>\n

Compound 11c (1.4g, 5.0mmol),1-(4-Bromophenyl)-1-methyl-1H-pyrazole(1.2g, 5.0mmol), catalyst Pd(dba)2 (144mg, 0.25mmol), tri-tert-butylphosphine (101mg, 0.5mmol), sodium tert-butoxide (576mg, 6.0mmol) were dissolved in toluene (50ml) The temperature was raised to 100C and the reaction was stirred for 12 hours. The reaction was detected by TLC, and directly concentrated by column chromatography to obtain 1.4g of off-white solid with a yield of 63.1%.<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-(4-Bromophenyl)-1-methyl-1H-pyrazole, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-(4-Bromophenyl)-1-methyl-1H-pyrazole, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[367,131],"tags":[127],"class_list":["post-1746","post","type-post","status-publish","format-standard","hentry","category-1191616-45-1","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nDiscovery of 1191616-45-1<\/title>\n<meta name=\"description\" content=\"Synthetic Route of 1191616-45-1, The chemical industry reduces the impact on the environment during synthesis 1191616-45-1, name is 4-(4-Bromophenyl)-1-methyl-1H-pyrazole, I believe this compound will play a more active role in future production and life.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1746\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Discovery of 1191616-45-1\" \/>\n<meta property=\"og:description\" content=\"Synthetic Route of 1191616-45-1, The chemical industry reduces the impact on the environment during synthesis 1191616-45-1, name is 4-(4-Bromophenyl)-1-methyl-1H-pyrazole, I believe this compound will play a more active role in future production and life.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1746\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-02-09T21:17:53+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1746\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1746\",\"name\":\"Discovery of 1191616-45-1\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-02-09T21:17:53+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Synthetic Route of 1191616-45-1, The chemical industry reduces the impact on the environment during synthesis 1191616-45-1, name is 4-(4-Bromophenyl)-1-methyl-1H-pyrazole, I believe this compound will play a more active role in future production and life.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1746#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=1746\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=1746#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Discovery of 1191616-45-1\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Discovery of 1191616-45-1","description":"Synthetic Route of 1191616-45-1, The chemical industry reduces the impact on the environment during synthesis 1191616-45-1, name is 4-(4-Bromophenyl)-1-methyl-1H-pyrazole, I believe this compound will play a more active role in future production and life.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=1746","og_locale":"en_US","og_type":"article","og_title":"Discovery of 1191616-45-1","og_description":"Synthetic Route of 1191616-45-1, The chemical industry reduces the impact on the environment during synthesis 1191616-45-1, name is 4-(4-Bromophenyl)-1-methyl-1H-pyrazole, I believe this compound will play a more active role in future production and life.","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=1746","og_site_name":"pyrazoles-derivatives","article_published_time":"2021-02-09T21:17:53+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=1746","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=1746","name":"Discovery of 1191616-45-1","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2021-02-09T21:17:53+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Synthetic Route of 1191616-45-1, The chemical industry reduces the impact on the environment during synthesis 1191616-45-1, name is 4-(4-Bromophenyl)-1-methyl-1H-pyrazole, I believe this compound will play a more active role in future production and life.","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=1746#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=1746"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=1746#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Discovery of 1191616-45-1"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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