{"id":1725,"date":"2021-02-09T05:19:50","date_gmt":"2021-02-08T21:19:50","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1725"},"modified":"2021-02-09T05:19:50","modified_gmt":"2021-02-08T21:19:50","slug":"the-origin-of-a-common-compound-about-20583-33-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1725","title":{"rendered":"The origin of a common compound about 20583-33-9"},"content":{"rendered":"

Application of 20583-33-9<\/a>, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 20583-33-9 name is 1-(1H-Pyrazol-3-yl)ethanone, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.<\/p>\n

Reference Synthesis Example 118 (0768) 3-(1,1-Difluoroethyl)-1H-pyrazole (0769) To a dichloroethane solution (6.0 mL) of 1-(1H-pyrazol-3-yl)ethanone (300 mg, 2.73 mmol) and bis(2-methoxyethyl))amino-sulfur trifluoride (1.11 mL, 5.99 mmol), one drop of ethanol was added at 0 C. and the resultant mixture was stirred at room temperature for 1 hour and 30 minutes. After completion of the reaction, the reaction solution was added dropwise to saturated sodium bicarbonate aqueous solution at 0 C. After adding dichloromethane, the resultant mixture was washed with saturated sodium chloride aqueous solution. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The obtained residue was purified by column chromatography (hexane\/ethyl acetate=3\/1) to obtain the title compound (145 mg, yield 41%).<\/p>\n

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-(1H-Pyrazol-3-yl)ethanone, and friends who are interested can also refer to it.<\/p>\n","protected":false},"excerpt":{"rendered":"

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-(1H-Pyrazol-3-yl)ethanone, and friends who are interested can also refer to it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[363,131],"tags":[126],"class_list":["post-1725","post","type-post","status-publish","format-standard","hentry","category-20583-33-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe origin of a common compound about 20583-33-9<\/title>\n<meta name=\"description\" content=\"Application of 20583-33-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 20583-33-9 name is 1-(1H-Pyrazol-3-yl)ethanone, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=1725\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The origin of a common compound about 20583-33-9\" \/>\n<meta property=\"og:description\" content=\"Application of 20583-33-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 20583-33-9 name is 1-(1H-Pyrazol-3-yl)ethanone, This compound is widely used in many fields, so it is necessary to find a new synthetic route. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The origin of a common compound about 20583-33-9","description":"Application of 20583-33-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 20583-33-9 name is 1-(1H-Pyrazol-3-yl)ethanone, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"http:\/\/www.pyrazoles-derivatives.com\/?p=1725","og_locale":"en_US","og_type":"article","og_title":"The origin of a common compound about 20583-33-9","og_description":"Application of 20583-33-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 20583-33-9 name is 1-(1H-Pyrazol-3-yl)ethanone, This compound is widely used in many fields, so it is necessary to find a new synthetic route. 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