{"id":1692,"date":"2021-02-08T05:02:59","date_gmt":"2021-02-07T21:02:59","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1692"},"modified":"2021-02-08T05:02:59","modified_gmt":"2021-02-07T21:02:59","slug":"brief-introduction-of-1260243-04-6-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1692","title":{"rendered":"Brief introduction of 1260243-04-6"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1260243-04-6, name is Ethyl 5-amino-1H-pyrazole-4-carboxylate, A new synthetic method of this compound is introduced below., COA of Formula: C6H9N3O2<\/a><\/p>\n

To a solution of ethyl 5-amino-lH-pyrazole-4-carboxylate (1.0 g, 6.45 mmol) in n- BuOH (1 ml) was added to ethyl 3-(2H-l,3-benzodioxol-5-yl)-3-oxopropanoate (1.83 g, 7.75 mmol and TsOH (55 mg, 0.32 mmol), and the reaction mixture was stirred for 20 h at 130C. The solid was collected by filtration and washed with methanol (3 x 10 ml) and dried in an oven under reduced pressure to afford ethyl 5- (2H-l,3-benzodioxol-5-yl)-7-oxo-4H,7H-pyrazolo[l,5-a]pyrimidine-3-carboxylate as a yellow solid (1.8 g, 85 ). LC\/MS (ES, m\/z): [M+H]+ 328.0 *H NMR (300 MHz, DMSO) delta 11.52 (s, 1H), 8.25 (s, 1H), 7.39 (d, \/= 1.8 Hz, 1H), 7.31 – 7.35 (m, 1H), 7.12 (d, \/= 8.1 Hz, 1H ), 6.23 (s, 1H), 6.16 (s, 2H), 4.28 – 4.35 (m, 2H), 1.32 – 1.37 (t, \/ = 7.2 Hz, 3H)<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[213,131],"tags":[126],"class_list":["post-1692","post","type-post","status-publish","format-standard","hentry","category-1260243-04-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nBrief introduction of 1260243-04-6<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1260243-04-6, name is Ethyl 5-amino-1H-pyrazole-4-carboxylate, A new synthetic method of this compound is introduced below., COA of Formula: C6H9N3O2\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1692\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brief introduction of 1260243-04-6\" \/>\n<meta property=\"og:description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Brief introduction of 1260243-04-6","description":"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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