{"id":1675,"date":"2021-02-07T05:53:05","date_gmt":"2021-02-06T21:53:05","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1675"},"modified":"2021-02-07T05:53:05","modified_gmt":"2021-02-06T21:53:05","slug":"introduction-of-a-new-synthetic-route-about-174891-10-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1675","title":{"rendered":"Introduction of a new synthetic route about 174891-10-2"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 174891-10-2, name is 5-Amino-1H-pyrazole-3-acetic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 174891-10-2, Quality Control of 5-Amino-1H-pyrazole-3-acetic acid<\/a><\/p>\n

Compound 7 (96 g, 0.395 mol, 1.0 eq.) and compound 4 (83.5 g, 0.592 mol, 1.5 eq.) were suspended in 960 mL of AcOH at 18-2O0C. The suspension was heated to 100- 1020C, and stirred for 2.5 h at this temperature. The suspension was cooled down to 18-2O0C, and filtered. Filtrate cake was washed with 50 mL of AcOH, followed by 100 mL of EtOAc. Solid was collected and dried under vacuum at 5O0C (12 h) to give 136 g of compound 10 with 96.5% HPLC purity in 98.9% yield.<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Amino-1H-pyrazole-3-acetic acid, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Amino-1H-pyrazole-3-acetic acid, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[350,131],"tags":[126],"class_list":["post-1675","post","type-post","status-publish","format-standard","hentry","category-174891-10-2","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nIntroduction of a new synthetic route about 174891-10-2<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 174891-10-2, name is 5-Amino-1H-pyrazole-3-acetic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Introduction of a new synthetic route about 174891-10-2","description":"Adding a certain compound to certain chemical reactions, such as: 174891-10-2, name is 5-Amino-1H-pyrazole-3-acetic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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